In vivo evidence that the cannabinoid receptor 2–63 RR variant is associated with the acquisition and/or expansion of HIV infection

C Sagnelli, C Uberti-Foppa, H Hasson, G Bellini, C Minichini, S Salpietro, E Messina, D Barbanotti, M Merli, F Punzo, N Coppola, A Lazzarin, E Sagnelli, F Rossi

Research output: Contribution to journalArticle

Abstract

Objectives: The aim of the study was to investigate whether the rs35761398 variants of the cannabinoid receptor 2 (CB2) gene may influence the acquisition of HIV infection and the clinical presentation of HIV/hepatitis C virus (HCV) coinfection. Methods: We compared 166 HIV/HCV-coinfected patients with 186 HCV-monoinfected patients, all with biopsy-proven chronic hepatitis (using the Ishak scoring system), naïve for anti-HCV treatment and tested for the CB2 rs35761398 polymorphism (using the TaqMan assay). Results: The HIV/HCV-coinfected patients were more frequently male (P 
Original languageEnglish
Pages (from-to)597-604
Number of pages8
JournalHIV Medicine
Volume19
Issue number9
DOIs
Publication statusPublished - 2018

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Cannabinoid Receptors
Hepacivirus
HIV Infections
HIV
Chronic Hepatitis
Coinfection
Biopsy
Genes

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In vivo evidence that the cannabinoid receptor 2–63 RR variant is associated with the acquisition and/or expansion of HIV infection. / Sagnelli, C; Uberti-Foppa, C; Hasson, H; Bellini, G; Minichini, C; Salpietro, S; Messina, E; Barbanotti, D; Merli, M; Punzo, F; Coppola, N; Lazzarin, A; Sagnelli, E; Rossi, F.

In: HIV Medicine, Vol. 19, No. 9, 2018, p. 597-604.

Research output: Contribution to journalArticle

Sagnelli, C, Uberti-Foppa, C, Hasson, H, Bellini, G, Minichini, C, Salpietro, S, Messina, E, Barbanotti, D, Merli, M, Punzo, F, Coppola, N, Lazzarin, A, Sagnelli, E & Rossi, F 2018, 'In vivo evidence that the cannabinoid receptor 2–63 RR variant is associated with the acquisition and/or expansion of HIV infection', HIV Medicine, vol. 19, no. 9, pp. 597-604. https://doi.org/10.1111/hiv.12638
Sagnelli, C ; Uberti-Foppa, C ; Hasson, H ; Bellini, G ; Minichini, C ; Salpietro, S ; Messina, E ; Barbanotti, D ; Merli, M ; Punzo, F ; Coppola, N ; Lazzarin, A ; Sagnelli, E ; Rossi, F. / In vivo evidence that the cannabinoid receptor 2–63 RR variant is associated with the acquisition and/or expansion of HIV infection. In: HIV Medicine. 2018 ; Vol. 19, No. 9. pp. 597-604.
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AU - Hasson, H

AU - Bellini, G

AU - Minichini, C

AU - Salpietro, S

AU - Messina, E

AU - Barbanotti, D

AU - Merli, M

AU - Punzo, F

AU - Coppola, N

AU - Lazzarin, A

AU - Sagnelli, E

AU - Rossi, F

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