IN VIVO EXPERIMENTAL EVALUATION OF BIOPROSTHETIC CARDIAC VALVES.

Michael Jones, Eloisa Arbustini, Elling E. Eidbo, Victor J. Ferrans

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

During the past 4 years an animal model system has been developed in juvenile (10-15) week old sheep which permits early and late studies of host-prosthesis interactions. Over 300 porcine aortic valves (PAV) and bovine pericardial valves (BPV) have been implanted in the tricuspid (TVR) or mitral (MVR) positions. Long-term survival (30 days-1 year) in the last 200 animals has been greater than 90%. In analyzing the results obtained with valve implantations in this model system, emphasis has been given to: 1) early and late hemodynamic investigations of valve function; 2) pathologic alterations, including localization of calcific deposits; 3) quantitative analysis of valve calcification; 4) evaluations of treatment processes to decrease valve calcification; and 5) use of intracardiac Doppler/2-D echocardiography to study valve function.

Original languageEnglish
Title of host publicationUnknown Host Publication Title
PublisherAssoc for the Advancement of Medical Instrumentation
Pages40
Number of pages1
ISBN (Print)0910275343
Publication statusPublished - 1984

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Animals
Echocardiography
Hemodynamics
Deposits
Chemical analysis
Prostheses and Implants

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Jones, M., Arbustini, E., Eidbo, E. E., & Ferrans, V. J. (1984). IN VIVO EXPERIMENTAL EVALUATION OF BIOPROSTHETIC CARDIAC VALVES. In Unknown Host Publication Title (pp. 40). Assoc for the Advancement of Medical Instrumentation.

IN VIVO EXPERIMENTAL EVALUATION OF BIOPROSTHETIC CARDIAC VALVES. / Jones, Michael; Arbustini, Eloisa; Eidbo, Elling E.; Ferrans, Victor J.

Unknown Host Publication Title. Assoc for the Advancement of Medical Instrumentation, 1984. p. 40.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Jones, M, Arbustini, E, Eidbo, EE & Ferrans, VJ 1984, IN VIVO EXPERIMENTAL EVALUATION OF BIOPROSTHETIC CARDIAC VALVES. in Unknown Host Publication Title. Assoc for the Advancement of Medical Instrumentation, pp. 40.
Jones M, Arbustini E, Eidbo EE, Ferrans VJ. IN VIVO EXPERIMENTAL EVALUATION OF BIOPROSTHETIC CARDIAC VALVES. In Unknown Host Publication Title. Assoc for the Advancement of Medical Instrumentation. 1984. p. 40
Jones, Michael ; Arbustini, Eloisa ; Eidbo, Elling E. ; Ferrans, Victor J. / IN VIVO EXPERIMENTAL EVALUATION OF BIOPROSTHETIC CARDIAC VALVES. Unknown Host Publication Title. Assoc for the Advancement of Medical Instrumentation, 1984. pp. 40
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