Abstract
During the past 4 years an animal model system has been developed in juvenile (10-15) week old sheep which permits early and late studies of host-prosthesis interactions. Over 300 porcine aortic valves (PAV) and bovine pericardial valves (BPV) have been implanted in the tricuspid (TVR) or mitral (MVR) positions. Long-term survival (30 days-1 year) in the last 200 animals has been greater than 90%. In analyzing the results obtained with valve implantations in this model system, emphasis has been given to: 1) early and late hemodynamic investigations of valve function; 2) pathologic alterations, including localization of calcific deposits; 3) quantitative analysis of valve calcification; 4) evaluations of treatment processes to decrease valve calcification; and 5) use of intracardiac Doppler/2-D echocardiography to study valve function.
| Original language | English |
|---|---|
| Title of host publication | Unknown Host Publication Title |
| Publisher | Assoc for the Advancement of Medical Instrumentation |
| Pages | 40 |
| Number of pages | 1 |
| ISBN (Print) | 0910275343 |
| Publication status | Published - 1984 |
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ASJC Scopus subject areas
- Engineering(all)
Cite this
IN VIVO EXPERIMENTAL EVALUATION OF BIOPROSTHETIC CARDIAC VALVES. / Jones, Michael; Arbustini, Eloisa; Eidbo, Elling E.; Ferrans, Victor J.
Unknown Host Publication Title. Assoc for the Advancement of Medical Instrumentation, 1984. p. 40.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - IN VIVO EXPERIMENTAL EVALUATION OF BIOPROSTHETIC CARDIAC VALVES.
AU - Jones, Michael
AU - Arbustini, Eloisa
AU - Eidbo, Elling E.
AU - Ferrans, Victor J.
PY - 1984
Y1 - 1984
N2 - During the past 4 years an animal model system has been developed in juvenile (10-15) week old sheep which permits early and late studies of host-prosthesis interactions. Over 300 porcine aortic valves (PAV) and bovine pericardial valves (BPV) have been implanted in the tricuspid (TVR) or mitral (MVR) positions. Long-term survival (30 days-1 year) in the last 200 animals has been greater than 90%. In analyzing the results obtained with valve implantations in this model system, emphasis has been given to: 1) early and late hemodynamic investigations of valve function; 2) pathologic alterations, including localization of calcific deposits; 3) quantitative analysis of valve calcification; 4) evaluations of treatment processes to decrease valve calcification; and 5) use of intracardiac Doppler/2-D echocardiography to study valve function.
AB - During the past 4 years an animal model system has been developed in juvenile (10-15) week old sheep which permits early and late studies of host-prosthesis interactions. Over 300 porcine aortic valves (PAV) and bovine pericardial valves (BPV) have been implanted in the tricuspid (TVR) or mitral (MVR) positions. Long-term survival (30 days-1 year) in the last 200 animals has been greater than 90%. In analyzing the results obtained with valve implantations in this model system, emphasis has been given to: 1) early and late hemodynamic investigations of valve function; 2) pathologic alterations, including localization of calcific deposits; 3) quantitative analysis of valve calcification; 4) evaluations of treatment processes to decrease valve calcification; and 5) use of intracardiac Doppler/2-D echocardiography to study valve function.
UR - http://www.scopus.com/inward/record.url?scp=0021600071&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021600071&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:0021600071
SN - 0910275343
SP - 40
BT - Unknown Host Publication Title
PB - Assoc for the Advancement of Medical Instrumentation
ER -