In vivo hydration and water-retention capacity of stratum corneum in clinically uninvolved skin in atopic and psoriatic patients

E. Berardesca, D. Fideli, G. Borroni, G. Rabbiosi, H. Maibach

Research output: Contribution to journalArticle

124 Citations (Scopus)

Abstract

Hydration and the water-retention capacity of stratum corneum have been investigated in uninvolved psoriatic and atopic skin and compared with that of healthy controls. Thirty-three subjects of either sex and matched for age entered the study. The subjects were free from all signs of skin disease and skin dryness. Hydration was evaluated by means of transepidermal water loss and skin capacitance measurements. Water-retention capacity was investigated using the plastic occlusion stress test. Atopic skin differed significantly from uninvolved psoriatic and control skin which had a reduced water content and an increased transepidermal water loss. Furthermore, the skin surface water loss profile representing the stratum corneum water-retention capacity was significantly lower in normal atopic skin. The data suggest that clinically normal skin may be functionally abnormal, resulting in a defective barrier that could lead to higher risk of irritant or contact dermatitis.

Original languageEnglish
Pages (from-to)400-404
Number of pages5
JournalActa Dermato-Venereologica
Volume70
Issue number5
Publication statusPublished - 1990

Fingerprint

social stratum
Cornea
water
Skin
Water
skin disease
Irritant Dermatitis
Hydration
Contact Dermatitis
Exercise Test
Skin Diseases
Plastics
contact

Keywords

  • Occlusion
  • Skin surface water loss

ASJC Scopus subject areas

  • Dermatology

Cite this

In vivo hydration and water-retention capacity of stratum corneum in clinically uninvolved skin in atopic and psoriatic patients. / Berardesca, E.; Fideli, D.; Borroni, G.; Rabbiosi, G.; Maibach, H.

In: Acta Dermato-Venereologica, Vol. 70, No. 5, 1990, p. 400-404.

Research output: Contribution to journalArticle

Berardesca, E, Fideli, D, Borroni, G, Rabbiosi, G & Maibach, H 1990, 'In vivo hydration and water-retention capacity of stratum corneum in clinically uninvolved skin in atopic and psoriatic patients', Acta Dermato-Venereologica, vol. 70, no. 5, pp. 400-404.
Berardesca, E. ; Fideli, D. ; Borroni, G. ; Rabbiosi, G. ; Maibach, H. / In vivo hydration and water-retention capacity of stratum corneum in clinically uninvolved skin in atopic and psoriatic patients. In: Acta Dermato-Venereologica. 1990 ; Vol. 70, No. 5. pp. 400-404.
@article{d8591def99d14f9db2431ad02d730b18,
title = "In vivo hydration and water-retention capacity of stratum corneum in clinically uninvolved skin in atopic and psoriatic patients",
abstract = "Hydration and the water-retention capacity of stratum corneum have been investigated in uninvolved psoriatic and atopic skin and compared with that of healthy controls. Thirty-three subjects of either sex and matched for age entered the study. The subjects were free from all signs of skin disease and skin dryness. Hydration was evaluated by means of transepidermal water loss and skin capacitance measurements. Water-retention capacity was investigated using the plastic occlusion stress test. Atopic skin differed significantly from uninvolved psoriatic and control skin which had a reduced water content and an increased transepidermal water loss. Furthermore, the skin surface water loss profile representing the stratum corneum water-retention capacity was significantly lower in normal atopic skin. The data suggest that clinically normal skin may be functionally abnormal, resulting in a defective barrier that could lead to higher risk of irritant or contact dermatitis.",
keywords = "Occlusion, Skin surface water loss",
author = "E. Berardesca and D. Fideli and G. Borroni and G. Rabbiosi and H. Maibach",
year = "1990",
language = "English",
volume = "70",
pages = "400--404",
journal = "Acta Borealia",
issn = "0001-5555",
publisher = "Society for the Publication of Acta Dermato-Venereologica",
number = "5",

}

TY - JOUR

T1 - In vivo hydration and water-retention capacity of stratum corneum in clinically uninvolved skin in atopic and psoriatic patients

AU - Berardesca, E.

AU - Fideli, D.

AU - Borroni, G.

AU - Rabbiosi, G.

AU - Maibach, H.

PY - 1990

Y1 - 1990

N2 - Hydration and the water-retention capacity of stratum corneum have been investigated in uninvolved psoriatic and atopic skin and compared with that of healthy controls. Thirty-three subjects of either sex and matched for age entered the study. The subjects were free from all signs of skin disease and skin dryness. Hydration was evaluated by means of transepidermal water loss and skin capacitance measurements. Water-retention capacity was investigated using the plastic occlusion stress test. Atopic skin differed significantly from uninvolved psoriatic and control skin which had a reduced water content and an increased transepidermal water loss. Furthermore, the skin surface water loss profile representing the stratum corneum water-retention capacity was significantly lower in normal atopic skin. The data suggest that clinically normal skin may be functionally abnormal, resulting in a defective barrier that could lead to higher risk of irritant or contact dermatitis.

AB - Hydration and the water-retention capacity of stratum corneum have been investigated in uninvolved psoriatic and atopic skin and compared with that of healthy controls. Thirty-three subjects of either sex and matched for age entered the study. The subjects were free from all signs of skin disease and skin dryness. Hydration was evaluated by means of transepidermal water loss and skin capacitance measurements. Water-retention capacity was investigated using the plastic occlusion stress test. Atopic skin differed significantly from uninvolved psoriatic and control skin which had a reduced water content and an increased transepidermal water loss. Furthermore, the skin surface water loss profile representing the stratum corneum water-retention capacity was significantly lower in normal atopic skin. The data suggest that clinically normal skin may be functionally abnormal, resulting in a defective barrier that could lead to higher risk of irritant or contact dermatitis.

KW - Occlusion

KW - Skin surface water loss

UR - http://www.scopus.com/inward/record.url?scp=0025148761&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025148761&partnerID=8YFLogxK

M3 - Article

VL - 70

SP - 400

EP - 404

JO - Acta Borealia

JF - Acta Borealia

SN - 0001-5555

IS - 5

ER -