"In vivo" imaging of atherosclerosis

Augusto Gallino, Matthias Stuber, Filippo Crea, Erling Falk, Roberto Corti, John Lekakis, Jürg Schwitter, Paolo Camici, Oliver Gaemperli, Marcello Di Valentino, John Prior, Hector M. Garcia-Garcia, Charalambos Vlachopoulos, Francesco Cosentino, Stephan Windecker, Giovanni Pedrazzini, Richard Conti, François Mach, Raffaele De Caterina, Peter Libby

Research output: Contribution to journalArticle

Abstract

Atherosclerosis is a systemic and multifocal disease, which starts early in life, and that usually takes decades before overt disease eventually appears as a consequence of progressive obstruction or abrupt thrombotic occlusion. This silent course makes necessary to develop predictors of disease long before symptomatic lesions develop. Besides several classical risk factors and new emerging humoral risk predictors, imaging may constitute a formidable diagnostic and prognostic tool in order to identify presence, extension, progression (or regression) of disease as well as vulnerability of atherosclerotic lesions. This review summarizes the rapidly growing clinical and research field in imaging atherosclerosis from different perspectives opening important opportunities for timely detection and treatment of atherosclerosis.

Original languageEnglish
Pages (from-to)25-36
Number of pages12
JournalAtherosclerosis
Volume224
Issue number1
DOIs
Publication statusPublished - Sep 2012

Keywords

  • Atherosclerosis
  • Imaging

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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    Gallino, A., Stuber, M., Crea, F., Falk, E., Corti, R., Lekakis, J., Schwitter, J., Camici, P., Gaemperli, O., Di Valentino, M., Prior, J., Garcia-Garcia, H. M., Vlachopoulos, C., Cosentino, F., Windecker, S., Pedrazzini, G., Conti, R., Mach, F., De Caterina, R., & Libby, P. (2012). "In vivo" imaging of atherosclerosis. Atherosclerosis, 224(1), 25-36. https://doi.org/10.1016/j.atherosclerosis.2012.04.007