In vivo spectrophotometric evaluation of neoplastic and non-neoplastic skin pigmented lesions--I. Reflectance measurements.

R. Marchesini, M. Brambilla, C. Clemente, M. Maniezzo, A. E. Sichirollo, A. Testori, D. R. Venturoli, N. Cascinelli

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

Reflectance spectrophotometry from 400 to 800 nm on different cutaneous pigmented lesions, including primary and metastatic malignant melanoma, pigmented nevi, lentigo and seborrhoeic keratosis, has been performed by using an external integrating sphere coupled to a spectrophotometer. Measurements show that reflectance spectra of the different lesions manifest dissimilar patterns, particularly in the near IR region. Comparison of reflectance of nevi with that of malignant melanomas results in a highly significant difference (P less than 10(-6)) between the two samples. Though interpretation of the spectra remains difficult as a result of the complexity of the optical processes of scattering and absorption, our results suggest that a detailed analysis of the reflectance spectrum may give clinically useful information, and could be utilized as an aid in clinical diagnosis of cutaneous pigmented lesions, especially where malignant melanoma is concerned.

Original languageEnglish
Pages (from-to)77-84
Number of pages8
JournalPhotochemistry and Photobiology
Volume53
Issue number1
Publication statusPublished - Jan 1991

Fingerprint

Reflectometers
lesions
Melanoma
Skin
reflectance
evaluation
Optical Phenomena
Lentigo
Keratosis
Pigmented Nevus
Nevus
Spectrophotometry
Spectrophotometers
Spectrum Analysis
spectrophotometers
spectrophotometry
Scattering
scattering

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Biophysics

Cite this

Marchesini, R., Brambilla, M., Clemente, C., Maniezzo, M., Sichirollo, A. E., Testori, A., ... Cascinelli, N. (1991). In vivo spectrophotometric evaluation of neoplastic and non-neoplastic skin pigmented lesions--I. Reflectance measurements. Photochemistry and Photobiology, 53(1), 77-84.

In vivo spectrophotometric evaluation of neoplastic and non-neoplastic skin pigmented lesions--I. Reflectance measurements. / Marchesini, R.; Brambilla, M.; Clemente, C.; Maniezzo, M.; Sichirollo, A. E.; Testori, A.; Venturoli, D. R.; Cascinelli, N.

In: Photochemistry and Photobiology, Vol. 53, No. 1, 01.1991, p. 77-84.

Research output: Contribution to journalArticle

Marchesini, R, Brambilla, M, Clemente, C, Maniezzo, M, Sichirollo, AE, Testori, A, Venturoli, DR & Cascinelli, N 1991, 'In vivo spectrophotometric evaluation of neoplastic and non-neoplastic skin pigmented lesions--I. Reflectance measurements.', Photochemistry and Photobiology, vol. 53, no. 1, pp. 77-84.
Marchesini R, Brambilla M, Clemente C, Maniezzo M, Sichirollo AE, Testori A et al. In vivo spectrophotometric evaluation of neoplastic and non-neoplastic skin pigmented lesions--I. Reflectance measurements. Photochemistry and Photobiology. 1991 Jan;53(1):77-84.
Marchesini, R. ; Brambilla, M. ; Clemente, C. ; Maniezzo, M. ; Sichirollo, A. E. ; Testori, A. ; Venturoli, D. R. ; Cascinelli, N. / In vivo spectrophotometric evaluation of neoplastic and non-neoplastic skin pigmented lesions--I. Reflectance measurements. In: Photochemistry and Photobiology. 1991 ; Vol. 53, No. 1. pp. 77-84.
@article{30ac137311eb4ebfbfa494dc878442df,
title = "In vivo spectrophotometric evaluation of neoplastic and non-neoplastic skin pigmented lesions--I. Reflectance measurements.",
abstract = "Reflectance spectrophotometry from 400 to 800 nm on different cutaneous pigmented lesions, including primary and metastatic malignant melanoma, pigmented nevi, lentigo and seborrhoeic keratosis, has been performed by using an external integrating sphere coupled to a spectrophotometer. Measurements show that reflectance spectra of the different lesions manifest dissimilar patterns, particularly in the near IR region. Comparison of reflectance of nevi with that of malignant melanomas results in a highly significant difference (P less than 10(-6)) between the two samples. Though interpretation of the spectra remains difficult as a result of the complexity of the optical processes of scattering and absorption, our results suggest that a detailed analysis of the reflectance spectrum may give clinically useful information, and could be utilized as an aid in clinical diagnosis of cutaneous pigmented lesions, especially where malignant melanoma is concerned.",
author = "R. Marchesini and M. Brambilla and C. Clemente and M. Maniezzo and Sichirollo, {A. E.} and A. Testori and Venturoli, {D. R.} and N. Cascinelli",
year = "1991",
month = "1",
language = "English",
volume = "53",
pages = "77--84",
journal = "Photochemistry and Photobiology",
issn = "0031-8655",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - In vivo spectrophotometric evaluation of neoplastic and non-neoplastic skin pigmented lesions--I. Reflectance measurements.

AU - Marchesini, R.

AU - Brambilla, M.

AU - Clemente, C.

AU - Maniezzo, M.

AU - Sichirollo, A. E.

AU - Testori, A.

AU - Venturoli, D. R.

AU - Cascinelli, N.

PY - 1991/1

Y1 - 1991/1

N2 - Reflectance spectrophotometry from 400 to 800 nm on different cutaneous pigmented lesions, including primary and metastatic malignant melanoma, pigmented nevi, lentigo and seborrhoeic keratosis, has been performed by using an external integrating sphere coupled to a spectrophotometer. Measurements show that reflectance spectra of the different lesions manifest dissimilar patterns, particularly in the near IR region. Comparison of reflectance of nevi with that of malignant melanomas results in a highly significant difference (P less than 10(-6)) between the two samples. Though interpretation of the spectra remains difficult as a result of the complexity of the optical processes of scattering and absorption, our results suggest that a detailed analysis of the reflectance spectrum may give clinically useful information, and could be utilized as an aid in clinical diagnosis of cutaneous pigmented lesions, especially where malignant melanoma is concerned.

AB - Reflectance spectrophotometry from 400 to 800 nm on different cutaneous pigmented lesions, including primary and metastatic malignant melanoma, pigmented nevi, lentigo and seborrhoeic keratosis, has been performed by using an external integrating sphere coupled to a spectrophotometer. Measurements show that reflectance spectra of the different lesions manifest dissimilar patterns, particularly in the near IR region. Comparison of reflectance of nevi with that of malignant melanomas results in a highly significant difference (P less than 10(-6)) between the two samples. Though interpretation of the spectra remains difficult as a result of the complexity of the optical processes of scattering and absorption, our results suggest that a detailed analysis of the reflectance spectrum may give clinically useful information, and could be utilized as an aid in clinical diagnosis of cutaneous pigmented lesions, especially where malignant melanoma is concerned.

UR - http://www.scopus.com/inward/record.url?scp=0026053981&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026053981&partnerID=8YFLogxK

M3 - Article

C2 - 2027910

AN - SCOPUS:0026053981

VL - 53

SP - 77

EP - 84

JO - Photochemistry and Photobiology

JF - Photochemistry and Photobiology

SN - 0031-8655

IS - 1

ER -