Incidence and correlates of complex ventricular arrhythmias during dobutamine stress echocardiography after acute myocardial infarction

R. Bigi, N. Partesana, A. Verzoni, P. Bandini, M. Maffi, A. Longoni, G. Occhi, C. Fiorentini

Research output: Contribution to journalArticle

Abstract

Although previous studies have confirmed the safety of dobutamine stress echocardiography, complex ventricular arrhythmias have been reported. Our aim was (1) to identify the markers of increased arrhythmic risk during dobutamine stress echocardiography and (2) to assess whether the occurrence of major ventricular arrhythmias during the test may represent a clinically useful marker of electrical instability. Three hundred and seventy-seven consecutive survivors from acute myocardial infarction, off cardioactive therapy, underwent dobutamine stress echocardiography 11.4 days after the acute event, Holter monitoring with assessment of heart rate variability and echocardiographic determination of left ventricular ejection fraction. In addition, exercise stress testing, signal averaged ECG and coronary angiography were carried out, respectively, in 357, 150 and 273 patients. Ten subjects showed complex ventricular arrhythmias (eight non-sustained and one sustained ventricular tachycardia and one ventricular fibrillation) during dobutamine stress echocardiography (group A), whilst 366 did not (group B). Complex ventricular arrhythmias were detected by Holter monitoring in 8/10 patients in group A and 45/367 patients in group B (odds ratio 28.6, 95% CI 5.4-92.2) and by exercise testing in 4/10 patients in group A and 33/347 patients in group B (odds ratio 6.3, 95% CI 1.4-27.2). Ejection fraction

Original languageEnglish
Pages (from-to)1819-1824
Number of pages6
JournalEuropean Heart Journal
Volume16
Issue number12
Publication statusPublished - 1995

Keywords

  • Acute myocardial infarction
  • Dobutamine stress echocardiography
  • Ventricular arrhythmias

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Physiology

Fingerprint Dive into the research topics of 'Incidence and correlates of complex ventricular arrhythmias during dobutamine stress echocardiography after acute myocardial infarction'. Together they form a unique fingerprint.

  • Cite this