Incidence and management of noncancer pain in cancer patients referred to a radiotherapy center

Mariangela Massaccesi, Francesco Deodato, Luciana Caravatta, Gabriella MacChia, Gilbert D A Padula, Sonia Di Rito, Aynalem A. Woldemariam, Marco Rossi, Carlo Di Falco, Rosa Tambaro, Samantha Mignogna, Mariano Flocco, Fabio Pacelli, Vincenzo Valentini, Numa Cellini, Alessio G. Morganti

Research output: Contribution to journalArticlepeer-review


OBJECTIVES: The incidence of noncancer pain (NCP) in cancer patients is unknown. An analysis of incidence, severity, impact on quality of life (QoL), and appropriateness of NCP treatment in a cohort of cancer patients referred to a radiotherapy center is reported. MATERIALS AND METHODS: Pain was scored from 0 (absence) to 3 (severe) and the adequacy of analgesic therapy was evaluated according to International Guidelines. Correlation between Pain Management Index and World Health Organization Analgesic Ladder was used to analyze the appropriateness of NCP treatment. In addition, pain was differentiated according to its origin and types and a comparison was performed between cancer pain (CP) and NCP. RESULTS: A total of 903 patients were eligible and 865 (95.8%) were considered evaluable. Three hundred ninety-eight patients (46.0%) had pain. CP and NCP pain incidence was 11.2% and 34.8%, respectively. Pain intensity was higher in patients with CP versus NCP (P=0.021). A neuropathic pain lower incidence (P=0.024) in NCP versus CP was recorded. Moreover, NCP was more inadequately treated than CP (P

Original languageEnglish
Pages (from-to)944-947
Number of pages4
JournalClinical Journal of Pain
Issue number11
Publication statusPublished - Nov 2013


  • neoplastic
  • neuropathic
  • nociceptive
  • noncancer
  • pain
  • radiotherapy

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Clinical Neurology


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