TY - JOUR
T1 - Incidence and prevalence of hypothyroidism in patients affected by chronic heart failure
T2 - Role of amiodarone
AU - Triggiani, Vincenzo
AU - Iacoviello, Massimo
AU - Monzani, Fabio
AU - Puzzovivo, Agata
AU - Guida, Pietro
AU - Forleo, Cinzia
AU - Ciccone, Marco Matteo
AU - Catanzaro, Raffaella
AU - Tafaro, Emilio
AU - Licchelli, Brunella
AU - Giagulli, Vito Angelo
AU - Guastamacchia, Edoardo
AU - Favale, Stefano
PY - 2012/3
Y1 - 2012/3
N2 - Background: It has been demonstrated that hypothyroidism can lead to significant hemodynamic alterations favoring the onset of chronic heart failure (CHF) as well as its progression. Furthermore, amiodarone, an iodinecontaining antiarhythmic drug frequently used in CHF patients, is often the cause of primary hypothyroidism. Aim of the Study: To define the prevalence and incidence of hypothyroidism in a group of CHF outpatients in stable clinical conditions, with particular reference to the role of amiodarone therapy. Results: Among the 422 enrolled patients (326 males, aged 65±12 years), 51 (12%) had a previous diagnosis of hypothyroidism while 21 (5%) were newly diagnosed at the enrolment. Then, the overall prevalence of hypothyroidism at the first evaluation was 17% and, as expected, it was significantly higher in females than males (33% vs 13%; p
AB - Background: It has been demonstrated that hypothyroidism can lead to significant hemodynamic alterations favoring the onset of chronic heart failure (CHF) as well as its progression. Furthermore, amiodarone, an iodinecontaining antiarhythmic drug frequently used in CHF patients, is often the cause of primary hypothyroidism. Aim of the Study: To define the prevalence and incidence of hypothyroidism in a group of CHF outpatients in stable clinical conditions, with particular reference to the role of amiodarone therapy. Results: Among the 422 enrolled patients (326 males, aged 65±12 years), 51 (12%) had a previous diagnosis of hypothyroidism while 21 (5%) were newly diagnosed at the enrolment. Then, the overall prevalence of hypothyroidism at the first evaluation was 17% and, as expected, it was significantly higher in females than males (33% vs 13%; p
KW - Amiodarone
KW - Chronic heart failure
KW - Hypothyroidism
UR - http://www.scopus.com/inward/record.url?scp=84857131435&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84857131435&partnerID=8YFLogxK
M3 - Article
C2 - 22214334
AN - SCOPUS:84857131435
VL - 12
SP - 86
EP - 94
JO - Endocrine, Metabolic and Immune Disorders - Drug Targets
JF - Endocrine, Metabolic and Immune Disorders - Drug Targets
SN - 1871-5303
IS - 1
ER -