Incidence and prognosis of stroke in young adults: A population-based study in Ferrara, Italy

Elisabetta Groppo, Riccardo De Gennaro, Gino Granieri, Patrik Fazio, Edward Cesnik, Enrico Granieri, Ilaria Casetta

Research output: Contribution to journalArticlepeer-review


The reported annual incidence of juvenile stroke ranges from 9 to 47 cases per 100,000 inhabitants. We sought to estimate the incidence of first-ever stroke in young adults through a population-based stroke registry in a well-defined and stable population. We planned to collect all cases of new stroke in people aged 15-44 years in Ferrara, Italy, over the period 2002-2007. During the surveillance period, a first-ever stroke was diagnosed in 39 patients, giving a mean annual crude incidence rate of 12.1 cases per 100,000 person-years (95% CI 8.6-16.5), 9.1 when adjusted to the European population. The overall 30-day case fatality rate was 7.7, 21.4% for hemorrhagic stroke. The incidence rate was in the range of estimates detected in western countries. The case-fatality rate was lower than that reported in less recent studies. The stroke subtype predicted the probability of death and the outcome.

Original languageEnglish
Pages (from-to)53-58
Number of pages6
JournalNeurological Sciences
Issue number1
Publication statusPublished - Feb 2012


  • Incidence
  • Prognosis
  • Stroke
  • Young adults

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Dermatology


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