Incidence and relevance of acute kidney injury in patients hospitalized with acute coronary syndromes

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Abstract

Acute kidney injury (AKI) occurs frequently in patients with acute coronary syndromes (ACS) and is associated with adverse short- and long-term outcomes. To date, however, no standardized definition of AKI has been used for patients with ACS. As a result, information on its true incidence and the clinical and prognostic relevance according to the severity of renal function deterioration are still lacking. We retrospectively studied 3,210 patients with ACS. AKI was identified on the basis of the changes in serum creatinine during hospitalization according to the AKI Network criteria. Overall, 409 patients (13%) developed AKI: 262 (64%) had stage 1, 25 (6%) stage 2, and 122 (30%) stage 3 AKI. In-hospital mortality was greater in patients with AKI than in those without AKI (21% vs 1%; p

Original languageEnglish
Pages (from-to)816-822
Number of pages7
JournalThe American Journal of Cardiology
Volume111
Issue number6
DOIs
Publication statusPublished - 2013

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Acute Coronary Syndrome
Acute Kidney Injury
Incidence
Hospital Mortality
Creatinine
Hospitalization
Kidney
Serum

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

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title = "Incidence and relevance of acute kidney injury in patients hospitalized with acute coronary syndromes",
abstract = "Acute kidney injury (AKI) occurs frequently in patients with acute coronary syndromes (ACS) and is associated with adverse short- and long-term outcomes. To date, however, no standardized definition of AKI has been used for patients with ACS. As a result, information on its true incidence and the clinical and prognostic relevance according to the severity of renal function deterioration are still lacking. We retrospectively studied 3,210 patients with ACS. AKI was identified on the basis of the changes in serum creatinine during hospitalization according to the AKI Network criteria. Overall, 409 patients (13{\%}) developed AKI: 262 (64{\%}) had stage 1, 25 (6{\%}) stage 2, and 122 (30{\%}) stage 3 AKI. In-hospital mortality was greater in patients with AKI than in those without AKI (21{\%} vs 1{\%}; p",
author = "Giancarlo Marenzi and Angelo Cabiati and Bertoli, {Silvio V.} and Emilio Assanelli and Ivana Marana and {De Metrio}, Monica and Mara Rubino and Marco Moltrasio and Marco Grazi and Jeness Campodonico and Valentina Milazzo and Fabrizio Veglia and Gianfranco Lauri and Bartorelli, {Antonio L.}",
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T1 - Incidence and relevance of acute kidney injury in patients hospitalized with acute coronary syndromes

AU - Marenzi, Giancarlo

AU - Cabiati, Angelo

AU - Bertoli, Silvio V.

AU - Assanelli, Emilio

AU - Marana, Ivana

AU - De Metrio, Monica

AU - Rubino, Mara

AU - Moltrasio, Marco

AU - Grazi, Marco

AU - Campodonico, Jeness

AU - Milazzo, Valentina

AU - Veglia, Fabrizio

AU - Lauri, Gianfranco

AU - Bartorelli, Antonio L.

PY - 2013

Y1 - 2013

N2 - Acute kidney injury (AKI) occurs frequently in patients with acute coronary syndromes (ACS) and is associated with adverse short- and long-term outcomes. To date, however, no standardized definition of AKI has been used for patients with ACS. As a result, information on its true incidence and the clinical and prognostic relevance according to the severity of renal function deterioration are still lacking. We retrospectively studied 3,210 patients with ACS. AKI was identified on the basis of the changes in serum creatinine during hospitalization according to the AKI Network criteria. Overall, 409 patients (13%) developed AKI: 262 (64%) had stage 1, 25 (6%) stage 2, and 122 (30%) stage 3 AKI. In-hospital mortality was greater in patients with AKI than in those without AKI (21% vs 1%; p

AB - Acute kidney injury (AKI) occurs frequently in patients with acute coronary syndromes (ACS) and is associated with adverse short- and long-term outcomes. To date, however, no standardized definition of AKI has been used for patients with ACS. As a result, information on its true incidence and the clinical and prognostic relevance according to the severity of renal function deterioration are still lacking. We retrospectively studied 3,210 patients with ACS. AKI was identified on the basis of the changes in serum creatinine during hospitalization according to the AKI Network criteria. Overall, 409 patients (13%) developed AKI: 262 (64%) had stage 1, 25 (6%) stage 2, and 122 (30%) stage 3 AKI. In-hospital mortality was greater in patients with AKI than in those without AKI (21% vs 1%; p

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JO - American Journal of Cardiology

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