Incidence and relevance of acute kidney injury in patients hospitalized with acute coronary syndromes

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Acute kidney injury (AKI) occurs frequently in patients with acute coronary syndromes (ACS) and is associated with adverse short- and long-term outcomes. To date, however, no standardized definition of AKI has been used for patients with ACS. As a result, information on its true incidence and the clinical and prognostic relevance according to the severity of renal function deterioration are still lacking. We retrospectively studied 3,210 patients with ACS. AKI was identified on the basis of the changes in serum creatinine during hospitalization according to the AKI Network criteria. Overall, 409 patients (13%) developed AKI: 262 (64%) had stage 1, 25 (6%) stage 2, and 122 (30%) stage 3 AKI. In-hospital mortality was greater in patients with AKI than in those without AKI (21% vs 1%; p

Original languageEnglish
Pages (from-to)816-822
Number of pages7
JournalThe American Journal of Cardiology
Issue number6
Publication statusPublished - 2013


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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