Incidence of cancer in the course of chronic pancreatitis

Giorgio Talamini, Massimo Falconi, Claudio Bassi, Nora Sartori, Roberto Salvia, Erminia Caldiron, Luca Frulloni, Vincenzo Di Francesco, Bruna Vaona, Paolo Bovo, Italo Vantini, Paolo Pederzoli, Giorgio Cavallini

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVE: Chronic pancreatitis patients appear to present an increased incidence of pancreatic cancer. The aim of the study was to compare the incidence of cancer, whether pancreatic or extrapancreatic, in our chronic pancreatitis cases with that in the population of our region. METHODS: We analyzed 715 cases of chronic pancreatitis with a median follow-up of 10 yr (7287 person-years); during this observation period they developed 61 neoplasms, 14 of which were pancreatic cancers. The cancer incidence rates were compared, after correction for age and gender, with those of a tumour registry. RESULTS: We documented a significant increase in incidence of both extrapancreatic (Standardized Incidence Ratio [SIR], 1.5; 95% confidence interval [CI], 1.1-2.0; p

Original languageEnglish
Pages (from-to)1253-1260
Number of pages8
JournalAmerican Journal of Gastroenterology
Volume94
Issue number5
DOIs
Publication statusPublished - May 1999

ASJC Scopus subject areas

  • Gastroenterology

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