Abstract
Introduction. Because of the dynamic nature of frailty, prospective epidemiological data are essential to calibrate an adequate public health response. Methods. A systematic review of literature on frailty incidence was conducted within the European Joint Action ADVANTAGE. Results. Of the 6 studies included, only 3 were specifically aimed at estimating frailty incidence, and only 2 provided disaggregated results by at least gender. The mean followup length (1-22.2 years; median 5.1), sample size (74-6306 individuals), and age of participants (≥ 30-65) varied greatly across studies. The adoption of incidence proportions rather than rates further limited comparability of results. After removing one outlier, incidence ranged from 5% (follow-up 22.2 years; age ≥ 30) to 13% (follow-up 1 year, age ≥ 55). Conclusions. Well-designed prospective studies of frailty are necessary. To facilitate comparison across studies and over time, incidence should be estimated in person-time rate. Analyses of factors associated with the development of frailty are needed to identify high-risk groups.
| Original language | English |
|---|---|
| Pages (from-to) | 239-245 |
| Number of pages | 7 |
| Journal | Annali dell'Istituto Superiore di Sanita |
| Volume | 54 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Jan 1 2018 |
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Keywords
- Aging
- Epidemiology
- Frailty
- Public health
- Systematic review
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
Cite this
Incidence of frailty : A systematic review of scientific literature from a public health perspective. / Work Package 5 of the Joint Action ADVANTAGE.
In: Annali dell'Istituto Superiore di Sanita, Vol. 54, No. 3, 01.01.2018, p. 239-245.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Incidence of frailty
T2 - A systematic review of scientific literature from a public health perspective
AU - Work Package 5 of the Joint Action ADVANTAGE
AU - Galluzzo, Lucia
AU - O'Caoimh, Rónán
AU - Rodríguez-Laso, Ángel
AU - Beltzer, Nathalie
AU - Ranhoff, Anette Hylen
AU - Van Der Heyden, Johan
AU - Lamprini-Koula, Maria
AU - Ciutan, Marius
AU - López-Samaniego, Luz
AU - Liew, Aaron
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Introduction. Because of the dynamic nature of frailty, prospective epidemiological data are essential to calibrate an adequate public health response. Methods. A systematic review of literature on frailty incidence was conducted within the European Joint Action ADVANTAGE. Results. Of the 6 studies included, only 3 were specifically aimed at estimating frailty incidence, and only 2 provided disaggregated results by at least gender. The mean followup length (1-22.2 years; median 5.1), sample size (74-6306 individuals), and age of participants (≥ 30-65) varied greatly across studies. The adoption of incidence proportions rather than rates further limited comparability of results. After removing one outlier, incidence ranged from 5% (follow-up 22.2 years; age ≥ 30) to 13% (follow-up 1 year, age ≥ 55). Conclusions. Well-designed prospective studies of frailty are necessary. To facilitate comparison across studies and over time, incidence should be estimated in person-time rate. Analyses of factors associated with the development of frailty are needed to identify high-risk groups.
AB - Introduction. Because of the dynamic nature of frailty, prospective epidemiological data are essential to calibrate an adequate public health response. Methods. A systematic review of literature on frailty incidence was conducted within the European Joint Action ADVANTAGE. Results. Of the 6 studies included, only 3 were specifically aimed at estimating frailty incidence, and only 2 provided disaggregated results by at least gender. The mean followup length (1-22.2 years; median 5.1), sample size (74-6306 individuals), and age of participants (≥ 30-65) varied greatly across studies. The adoption of incidence proportions rather than rates further limited comparability of results. After removing one outlier, incidence ranged from 5% (follow-up 22.2 years; age ≥ 30) to 13% (follow-up 1 year, age ≥ 55). Conclusions. Well-designed prospective studies of frailty are necessary. To facilitate comparison across studies and over time, incidence should be estimated in person-time rate. Analyses of factors associated with the development of frailty are needed to identify high-risk groups.
KW - Aging
KW - Epidemiology
KW - Frailty
KW - Public health
KW - Systematic review
UR - http://www.scopus.com/inward/record.url?scp=85054099713&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85054099713&partnerID=8YFLogxK
U2 - 10.4415/ANN_18_03_11
DO - 10.4415/ANN_18_03_11
M3 - Article
C2 - 30284551
AN - SCOPUS:85054099713
VL - 54
SP - 239
EP - 245
JO - Annali dell'Istituto Superiore di Sanita
JF - Annali dell'Istituto Superiore di Sanita
SN - 0021-2571
IS - 3
ER -