Incidence of hemorrhagic cerebrovascular disease due to vascular malformations during the COVID-19 national quarantine in Italy

Pasquale De Bonis, Michele Alessandro Cavallo, Carmelo Lucio Sturiale, Cecilia Martellucci, Maria Elena Flacco, Michele Dughiero, Anna Maria Auricchio, Luca Ricciardi, Antonino Raco, Carlo Bortolotti, Luigino Tosatto, Marcello D'Andrea, Maria Ruggiero, Lorenzo Mongardi, Gianluigi Zona, Pietro Fiaschi, Fabio Cofano, Diego Garbossa, Alba Scerrati

Research output: Contribution to journalArticlepeer-review

Abstract

Background: hemorrhagic cerebrovascular disease due to vascular malformations represents an emergency for neurosurgery and neuro-interventional departments. During the COVID-19 pandemic, a dramatic reduction in the number of hospitalizations for acute myocardial infarction or stroke and a larger time interval from symptom onset to first medical contact have been reported. This study aims to verify the hypothesis that there would also have been a reduction of admissions for hemorrhagic cerebrovascular disease during the Italian lockdown. Material and method: s A multicenter, observational survey was conducted to collect data on hospital admissions for hemorrhagic cerebrovascular disease due to vascular malformations throughout two-months (March 15th to May 15th); the years 2020 (COVID-19 Italian lockdown), 2019 and 2018 were compared. Cases were identified by ICD-9 codes 430, 431, 432.1, 432.9, 747.81 of each hospital database. The statistical significance of the difference between the event rate of one year versus the others was evaluated using Poisson Means test, assuming a constant population. Results: During the 2020 lockdown, the total number of admissions for hemorrhagic cerebrovascular disease was 92 compared with 116 in 2019 and 95 in 2018. This difference was not significant. GCS upon admission was 3–8 in 44 % of cases in 2020 (41 patients), 39.7 % in 2019 (46 patients) and 28 % in 2018 (27 patients). Conclusion: Reduction of admissions for hemorrhagic cerebrovascular disease due to vascular malformations during the COVID-19 lockdown was not confirmed. Nevertheless, some patients reached the emergency rooms only several days after symptoms onset, resulting in a worse clinical condition at admission.

Original languageEnglish
Article number106503
JournalClinical Neurology and Neurosurgery
Volume202
DOIs
Publication statusPublished - Mar 2021

Keywords

  • Aneurysm
  • Arteriovenous malformation
  • Cavernoma
  • COVID-19
  • DAVF
  • Dural arteriovenous fistula
  • Hemorrhagic cerebrovascular disease
  • Subarachnoid hemorrhage
  • Vascular malformations

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Incidence of hemorrhagic cerebrovascular disease due to vascular malformations during the COVID-19 national quarantine in Italy'. Together they form a unique fingerprint.

Cite this