Incidence of malignancies in HIVinfected patients and prognostic role of current CD4 cell count: evidence from a large Italian cohort study

M. C F Prosperi, A. Cozzi-Lepri, A. Castagna, C. Mussini, R. Murri, A. Giacometti, C. Torti, A. Costantini, P. Narciso, F. Ghinelli, A. Antinori, A. D'Arminio Monforte

Research output: Contribution to journalArticlepeer-review

Abstract

The incidence of and predictors of acquired immunodeficiency syndrome-defining malignancies (ADMs) and nonADM (NADMs) were evaluated in a large Italian cohort. The incidence of ADM and NADM was 5.0 cases per 1000 personyears of follow-up (95% confidence interval, 4.3-5.8 cases per 1000 person-years of follow-up) and 2.4 cases per 1000 person-years of follow-up (95% confidence interval, 1.9-3.1 cases per 1000 person-years of follow-up), respectively. Lower current CD4 cell count was an independent predictor of developing malignancies, with the association being stronger for ADM than for NADM.

Original languageEnglish
Pages (from-to)1316-1321
Number of pages6
JournalClinical Infectious Diseases
Volume50
Issue number9
DOIs
Publication statusPublished - May 1 2010

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)
  • Medicine(all)

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