TY - JOUR
T1 - Incidence of Successful Pregnancy After Weight Loss Interventions in Infertile Women
T2 - a Systematic Review and Meta-Analysis of the Literature
AU - Milone, Marco
AU - de Placido, Giuseppe
AU - Musella, Mario
AU - Sosa Fernandez, Loredana Maria
AU - Sosa Fernandez, Laura Virginia
AU - Campana, Gabriele
AU - Di Minno, Matteo Nicola Dario
AU - Milone, Francesco
PY - 2015/12/12
Y1 - 2015/12/12
N2 - Little is known about the impact of weight loss interventions on pregnancy rate. A systematic review with meta-analysis of literature has been performed to evaluate the incidence of successful pregnancy after bariatric interventions in infertile women. By pooling together data from 589 infertile obese women, we have been able to provide an aggregate estimation of successful pregnancy after weight loss interventions. Our results showed an impressive high incidence (58 %) of infertile women who become spontaneously pregnant after surgery. Based on our results, bariatric interventions could be included in the treatment of obesity-related infertility. However, the results must be interpreted with caution owning to the quality of the data provided by included studies. Further ad hoc studies are needed to validate the effectiveness of bariatric interventions on reproductive function.
AB - Little is known about the impact of weight loss interventions on pregnancy rate. A systematic review with meta-analysis of literature has been performed to evaluate the incidence of successful pregnancy after bariatric interventions in infertile women. By pooling together data from 589 infertile obese women, we have been able to provide an aggregate estimation of successful pregnancy after weight loss interventions. Our results showed an impressive high incidence (58 %) of infertile women who become spontaneously pregnant after surgery. Based on our results, bariatric interventions could be included in the treatment of obesity-related infertility. However, the results must be interpreted with caution owning to the quality of the data provided by included studies. Further ad hoc studies are needed to validate the effectiveness of bariatric interventions on reproductive function.
KW - Bariatric
KW - BMI
KW - Fertility
KW - Infertility
KW - Obesity
UR - http://www.scopus.com/inward/record.url?scp=84949640950&partnerID=8YFLogxK
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U2 - 10.1007/s11695-015-1998-7
DO - 10.1007/s11695-015-1998-7
M3 - Article
C2 - 26661108
AN - SCOPUS:84949640950
SP - 1
EP - 9
JO - Obesity Surgery
JF - Obesity Surgery
SN - 0960-8923
ER -