Incidence of T cell subset imbalance in relatives of Graves’ disease patients

P. Biassoni; G. Ciprandi; S. Ferrini; G. Chimini; G. W. Canonica; M. Bagnasco

doi:10.1007/BF03348405

Incidence of T cell subset imbalance in relatives of Graves’ disease patients

P. Biassoni, G. Ciprandi, S. Ferrini, G. Chimini, G. W. Canonica, M. Bagnasco

A.O.U. San Martino - IST, Istituto Nazionale Ricerca sul Cancro (GENOVA)

Research output: Contribution to journal › Article › peer-review

Abstract

In previous reports we demonstrated imbalances of T cell subsets in patients with autoimmune thyroid disease. In the present investigation, we studied several T cell markers with different functional meaning (Fc γ-receptors, HLA-la antigens, MLR4 and 5/9 antigens) in first degree relatives of G raves’ disease patients. Our data suggest that imbalances of circulating T cell subpopulations are apparent only when abnormal hormone levels and/or thyroid autoantibodies are present.

Original language	English
Pages (from-to)	141-146
Number of pages	6
Journal	Journal of Endocrinological Investigation
Volume	7
Issue number	2
DOIs	https://doi.org/10.1007/BF03348405
Publication status	Published - 1984

Keywords

Fc γ-receptor
Graves’ disease
monoclonal antibodies
T cell subsets

ASJC Scopus subject areas

Endocrinology
Endocrinology, Diabetes and Metabolism

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10.1007/BF03348405

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title = "Incidence of T cell subset imbalance in relatives of Graves{\textquoteright} disease patients",

abstract = "In previous reports we demonstrated imbalances of T cell subsets in patients with autoimmune thyroid disease. In the present investigation, we studied several T cell markers with different functional meaning (Fc γ-receptors, HLA-la antigens, MLR4 and 5/9 antigens) in first degree relatives of G raves{\textquoteright} disease patients. Our data suggest that imbalances of circulating T cell subpopulations are apparent only when abnormal hormone levels and/or thyroid autoantibodies are present.",

keywords = "Fc γ-receptor, Graves{\textquoteright} disease, monoclonal antibodies, T cell subsets",

author = "P. Biassoni and G. Ciprandi and S. Ferrini and G. Chimini and Canonica, {G. W.} and M. Bagnasco",

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AU - Biassoni, P.

AU - Ciprandi, G.

AU - Ferrini, S.

AU - Chimini, G.

AU - Canonica, G. W.

AU - Bagnasco, M.

PY - 1984

Y1 - 1984

N2 - In previous reports we demonstrated imbalances of T cell subsets in patients with autoimmune thyroid disease. In the present investigation, we studied several T cell markers with different functional meaning (Fc γ-receptors, HLA-la antigens, MLR4 and 5/9 antigens) in first degree relatives of G raves’ disease patients. Our data suggest that imbalances of circulating T cell subpopulations are apparent only when abnormal hormone levels and/or thyroid autoantibodies are present.

AB - In previous reports we demonstrated imbalances of T cell subsets in patients with autoimmune thyroid disease. In the present investigation, we studied several T cell markers with different functional meaning (Fc γ-receptors, HLA-la antigens, MLR4 and 5/9 antigens) in first degree relatives of G raves’ disease patients. Our data suggest that imbalances of circulating T cell subpopulations are apparent only when abnormal hormone levels and/or thyroid autoantibodies are present.

KW - Fc γ-receptor

KW - Graves’ disease

KW - monoclonal antibodies

KW - T cell subsets

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Incidence of T cell subset imbalance in relatives of Graves’ disease patients

Abstract

Keywords

ASJC Scopus subject areas

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