Incidence of T cell subset imbalance in relatives of Graves’ disease patients

P. Biassoni, G. Ciprandi, S. Ferrini, G. Chimini, G. W. Canonica, M. Bagnasco

Research output: Contribution to journalArticlepeer-review

Abstract

In previous reports we demonstrated imbalances of T cell subsets in patients with autoimmune thyroid disease. In the present investigation, we studied several T cell markers with different functional meaning (Fc γ-receptors, HLA-la antigens, MLR4 and 5/9 antigens) in first degree relatives of G raves’ disease patients. Our data suggest that imbalances of circulating T cell subpopulations are apparent only when abnormal hormone levels and/or thyroid autoantibodies are present.

Original languageEnglish
Pages (from-to)141-146
Number of pages6
JournalJournal of Endocrinological Investigation
Volume7
Issue number2
DOIs
Publication statusPublished - 1984

Keywords

  • Fc γ-receptor
  • Graves’ disease
  • monoclonal antibodies
  • T cell subsets

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

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