Incidence, Patterns, and Associations Between Dual-Antiplatelet Therapy Cessation and Risk for Adverse Events Among Patients With and Without Diabetes Mellitus Receiving Drug-Eluting Stents: Results From the PARIS Registry

Michela Faggioni; U Baber; S Sartori; G Giustino; DJ Cohen; TD Henry; S Farhan; C Ariti; G Dangas; M Gibson; D Giacoppo; MW Krucoff; Melissa Aquino; J Chandrasekhar; DJ Moliterno; A Colombo; B Vogel; A Chieffo; AS Kini; B Witzenbichler; G Weisz; PG Steg; S Pocock; R Mehran

doi:10.1016/j.jcin.2016.12.003

Incidence, Patterns, and Associations Between Dual-Antiplatelet Therapy Cessation and Risk for Adverse Events Among Patients With and Without Diabetes Mellitus Receiving Drug-Eluting Stents: Results From the PARIS Registry

Michela Faggioni, U Baber, S Sartori, G Giustino, DJ Cohen, TD Henry, S Farhan, C Ariti, G Dangas, M Gibson, D Giacoppo, MW Krucoff, Melissa Aquino, J Chandrasekhar, DJ Moliterno, A Colombo, B Vogel, A Chieffo, AS Kini, B WitzenbichlerG Weisz, PG Steg, S Pocock, R Mehran

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Objectives The aim of this study was to examine the frequency and clinical impact of different cessation patterns of dual-antiplatelet therapy (DAPT) after percutaneous coronary intervention with drug-eluting stents among patients with and those without diabetes mellitus (DM). Background Early DAPT suspension after percutaneous coronary intervention increases the risk for major adverse cardiac events. However, temporal variability in risk and relation to DAPT cessation patterns among patients with DM remain unclear. Methods Using data from the PARIS (Patterns of Non-Adherence to Anti-Platelet Regimens in Stented Patients) registry, 1,430 patients with DM (34%) and 2,777 without DM (66%) treated with drug-eluting stents were identified. DAPT cessation modes were classified as temporary interruption (

Original language	English
Pages (from-to)	645-654
Number of pages	10
Journal	JACC: Cardiovascular Interventions
Volume	10
Issue number	7
DOIs	https://doi.org/10.1016/j.jcin.2016.12.003
Publication status	Published - 2017

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10.1016/j.jcin.2016.12.003

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Faggioni, M., Baber, U., Sartori, S., Giustino, G., Cohen, DJ., Henry, TD., Farhan, S., Ariti, C., Dangas, G., Gibson, M., Giacoppo, D., Krucoff, MW., Aquino, M., Chandrasekhar, J., Moliterno, DJ., Colombo, A., Vogel, B., Chieffo, A., Kini, AS., ... Mehran, R. (2017). Incidence, Patterns, and Associations Between Dual-Antiplatelet Therapy Cessation and Risk for Adverse Events Among Patients With and Without Diabetes Mellitus Receiving Drug-Eluting Stents: Results From the PARIS Registry. JACC: Cardiovascular Interventions, 10(7), 645-654. https://doi.org/10.1016/j.jcin.2016.12.003

Incidence, Patterns, and Associations Between Dual-Antiplatelet Therapy Cessation and Risk for Adverse Events Among Patients With and Without Diabetes Mellitus Receiving Drug-Eluting Stents: Results From the PARIS Registry. / Faggioni, Michela; Baber, U; Sartori, S; Giustino, G; Cohen, DJ; Henry, TD; Farhan, S; Ariti, C; Dangas, G; Gibson, M; Giacoppo, D; Krucoff, MW; Aquino, Melissa; Chandrasekhar, J; Moliterno, DJ; Colombo, A; Vogel, B; Chieffo, A; Kini, AS; Witzenbichler, B; Weisz, G; Steg, PG; Pocock, S; Mehran, R.

In: JACC: Cardiovascular Interventions, Vol. 10, No. 7, 2017, p. 645-654.

Research output: Contribution to journal › Article › peer-review

Faggioni, M, Baber, U, Sartori, S, Giustino, G, Cohen, DJ, Henry, TD, Farhan, S, Ariti, C, Dangas, G, Gibson, M, Giacoppo, D, Krucoff, MW, Aquino, M, Chandrasekhar, J, Moliterno, DJ, Colombo, A, Vogel, B, Chieffo, A, Kini, AS, Witzenbichler, B, Weisz, G, Steg, PG, Pocock, S & Mehran, R 2017, 'Incidence, Patterns, and Associations Between Dual-Antiplatelet Therapy Cessation and Risk for Adverse Events Among Patients With and Without Diabetes Mellitus Receiving Drug-Eluting Stents: Results From the PARIS Registry', JACC: Cardiovascular Interventions, vol. 10, no. 7, pp. 645-654. https://doi.org/10.1016/j.jcin.2016.12.003

Faggioni M, Baber U, Sartori S, Giustino G, Cohen DJ, Henry TD et al. Incidence, Patterns, and Associations Between Dual-Antiplatelet Therapy Cessation and Risk for Adverse Events Among Patients With and Without Diabetes Mellitus Receiving Drug-Eluting Stents: Results From the PARIS Registry. JACC: Cardiovascular Interventions. 2017;10(7):645-654. https://doi.org/10.1016/j.jcin.2016.12.003

Faggioni, Michela ; Baber, U ; Sartori, S ; Giustino, G ; Cohen, DJ ; Henry, TD ; Farhan, S ; Ariti, C ; Dangas, G ; Gibson, M ; Giacoppo, D ; Krucoff, MW ; Aquino, Melissa ; Chandrasekhar, J ; Moliterno, DJ ; Colombo, A ; Vogel, B ; Chieffo, A ; Kini, AS ; Witzenbichler, B ; Weisz, G ; Steg, PG ; Pocock, S ; Mehran, R. / Incidence, Patterns, and Associations Between Dual-Antiplatelet Therapy Cessation and Risk for Adverse Events Among Patients With and Without Diabetes Mellitus Receiving Drug-Eluting Stents: Results From the PARIS Registry. In: JACC: Cardiovascular Interventions. 2017 ; Vol. 10, No. 7. pp. 645-654.

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abstract = "Objectives The aim of this study was to examine the frequency and clinical impact of different cessation patterns of dual-antiplatelet therapy (DAPT) after percutaneous coronary intervention with drug-eluting stents among patients with and those without diabetes mellitus (DM). Background Early DAPT suspension after percutaneous coronary intervention increases the risk for major adverse cardiac events. However, temporal variability in risk and relation to DAPT cessation patterns among patients with DM remain unclear. Methods Using data from the PARIS (Patterns of Non-Adherence to Anti-Platelet Regimens in Stented Patients) registry, 1,430 patients with DM (34%) and 2,777 without DM (66%) treated with drug-eluting stents were identified. DAPT cessation modes were classified as temporary interruption (",

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T1 - Incidence, Patterns, and Associations Between Dual-Antiplatelet Therapy Cessation and Risk for Adverse Events Among Patients With and Without Diabetes Mellitus Receiving Drug-Eluting Stents: Results From the PARIS Registry

AU - Faggioni, Michela

AU - Baber, U

AU - Sartori, S

AU - Giustino, G

AU - Cohen, DJ

AU - Henry, TD

AU - Farhan, S

AU - Ariti, C

AU - Dangas, G

AU - Gibson, M

AU - Giacoppo, D

AU - Krucoff, MW

AU - Aquino, Melissa

AU - Chandrasekhar, J

AU - Moliterno, DJ

AU - Colombo, A

AU - Vogel, B

AU - Chieffo, A

AU - Kini, AS

AU - Witzenbichler, B

AU - Weisz, G

AU - Steg, PG

AU - Pocock, S

AU - Mehran, R

PY - 2017

Y1 - 2017

N2 - Objectives The aim of this study was to examine the frequency and clinical impact of different cessation patterns of dual-antiplatelet therapy (DAPT) after percutaneous coronary intervention with drug-eluting stents among patients with and those without diabetes mellitus (DM). Background Early DAPT suspension after percutaneous coronary intervention increases the risk for major adverse cardiac events. However, temporal variability in risk and relation to DAPT cessation patterns among patients with DM remain unclear. Methods Using data from the PARIS (Patterns of Non-Adherence to Anti-Platelet Regimens in Stented Patients) registry, 1,430 patients with DM (34%) and 2,777 without DM (66%) treated with drug-eluting stents were identified. DAPT cessation modes were classified as temporary interruption (

AB - Objectives The aim of this study was to examine the frequency and clinical impact of different cessation patterns of dual-antiplatelet therapy (DAPT) after percutaneous coronary intervention with drug-eluting stents among patients with and those without diabetes mellitus (DM). Background Early DAPT suspension after percutaneous coronary intervention increases the risk for major adverse cardiac events. However, temporal variability in risk and relation to DAPT cessation patterns among patients with DM remain unclear. Methods Using data from the PARIS (Patterns of Non-Adherence to Anti-Platelet Regimens in Stented Patients) registry, 1,430 patients with DM (34%) and 2,777 without DM (66%) treated with drug-eluting stents were identified. DAPT cessation modes were classified as temporary interruption (

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DO - 10.1016/j.jcin.2016.12.003

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SP - 645

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JO - JACC: Cardiovascular Interventions

JF - JACC: Cardiovascular Interventions

SN - 1936-8798

IS - 7

ER -