Gallbladder cancer is the most common malignant neoplasm of the biliary tract [1, 2]. The reported incidence of incidental gallbladder carcinoma during or after laparoscopic cholecystectomy ranges from 0.2% to 0.6% [3-5]. Most incidental gallbladder carcinomas are T1 (tumor invading the lamina propria or muscle layer). Despite recent progress in diagnostic techniques and equipment, preoperative diagnosis of gallbladder cancer is often difficult, especially if gallstone disease is present and tumor invasion is limited to the gallbladder wall . If gallbladder cancer is suspected intraoperatively, the diagnostic accuracy of the frozen section is high, but the frozen section yields less reliable information about the depth of tumor invasion (T) .
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