Incidental diagnosis of primary vaginal adenocarcinoma of intestinal type: A case report and review of the literature

Antonino Ditto, Fabio Martinelli, Maria Luisa Carcangiu, Francesco Hanozet, Eugenio Solima, Marta Barisella, Annamaria Cerrotta, Francesco Raspagliesi

Research output: Contribution to journalArticle

Abstract

Primary vaginal adenocarcinoma of intestinal type is a rare malignant gynecologic disease. A 53-year-old woman was admitted to our institution with a diagnosis of endometrial adenocarcinoma. A physical examination revealed a 2-cm polypoid lesion of the vagina. The patient underwent surgery for endometrial cancer and wedge resection of the vaginal lesion. The diagnosis of primary vaginal adenocarcinoma of intestinal type was obtained after standard and immunohistochemical analyses of the specimen. No endometrial cancer was detected in the specimen. Radiological investigations excluded metastasis from the gastrointestinal tract. Subsequently, the patient underwent concomitant chemoradiation. At present, 32 months later, she is well and disease-free. Extensive radiological investigations and careful immunohistochemical analysis of the specimen are needed for a correct diagnosis of vaginal adenocarcinoma of intestinal type. Concomitant chemoradiation, as a primary treatment, should be considered.

Original languageEnglish
Pages (from-to)490-493
Number of pages4
JournalInternational Journal of Gynecological Pathology
Volume26
Issue number4
DOIs
Publication statusPublished - Oct 2007

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Adenocarcinoma
Endometrial Neoplasms
Female Genital Diseases
Vagina
Physical Examination
Gastrointestinal Tract
Neoplasm Metastasis
Therapeutics

Keywords

  • Chemoradiation
  • Immunohistochemical analysis
  • Intestinal type
  • PET
  • Primary vaginal adenocarcinoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Obstetrics and Gynaecology

Cite this

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title = "Incidental diagnosis of primary vaginal adenocarcinoma of intestinal type: A case report and review of the literature",
abstract = "Primary vaginal adenocarcinoma of intestinal type is a rare malignant gynecologic disease. A 53-year-old woman was admitted to our institution with a diagnosis of endometrial adenocarcinoma. A physical examination revealed a 2-cm polypoid lesion of the vagina. The patient underwent surgery for endometrial cancer and wedge resection of the vaginal lesion. The diagnosis of primary vaginal adenocarcinoma of intestinal type was obtained after standard and immunohistochemical analyses of the specimen. No endometrial cancer was detected in the specimen. Radiological investigations excluded metastasis from the gastrointestinal tract. Subsequently, the patient underwent concomitant chemoradiation. At present, 32 months later, she is well and disease-free. Extensive radiological investigations and careful immunohistochemical analysis of the specimen are needed for a correct diagnosis of vaginal adenocarcinoma of intestinal type. Concomitant chemoradiation, as a primary treatment, should be considered.",
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author = "Antonino Ditto and Fabio Martinelli and Carcangiu, {Maria Luisa} and Francesco Hanozet and Eugenio Solima and Marta Barisella and Annamaria Cerrotta and Francesco Raspagliesi",
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T2 - A case report and review of the literature

AU - Ditto, Antonino

AU - Martinelli, Fabio

AU - Carcangiu, Maria Luisa

AU - Hanozet, Francesco

AU - Solima, Eugenio

AU - Barisella, Marta

AU - Cerrotta, Annamaria

AU - Raspagliesi, Francesco

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N2 - Primary vaginal adenocarcinoma of intestinal type is a rare malignant gynecologic disease. A 53-year-old woman was admitted to our institution with a diagnosis of endometrial adenocarcinoma. A physical examination revealed a 2-cm polypoid lesion of the vagina. The patient underwent surgery for endometrial cancer and wedge resection of the vaginal lesion. The diagnosis of primary vaginal adenocarcinoma of intestinal type was obtained after standard and immunohistochemical analyses of the specimen. No endometrial cancer was detected in the specimen. Radiological investigations excluded metastasis from the gastrointestinal tract. Subsequently, the patient underwent concomitant chemoradiation. At present, 32 months later, she is well and disease-free. Extensive radiological investigations and careful immunohistochemical analysis of the specimen are needed for a correct diagnosis of vaginal adenocarcinoma of intestinal type. Concomitant chemoradiation, as a primary treatment, should be considered.

AB - Primary vaginal adenocarcinoma of intestinal type is a rare malignant gynecologic disease. A 53-year-old woman was admitted to our institution with a diagnosis of endometrial adenocarcinoma. A physical examination revealed a 2-cm polypoid lesion of the vagina. The patient underwent surgery for endometrial cancer and wedge resection of the vaginal lesion. The diagnosis of primary vaginal adenocarcinoma of intestinal type was obtained after standard and immunohistochemical analyses of the specimen. No endometrial cancer was detected in the specimen. Radiological investigations excluded metastasis from the gastrointestinal tract. Subsequently, the patient underwent concomitant chemoradiation. At present, 32 months later, she is well and disease-free. Extensive radiological investigations and careful immunohistochemical analysis of the specimen are needed for a correct diagnosis of vaginal adenocarcinoma of intestinal type. Concomitant chemoradiation, as a primary treatment, should be considered.

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KW - Immunohistochemical analysis

KW - Intestinal type

KW - PET

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