Incisional recurrences after endometrial cancer surgery

Giorgio Bogani, Sean C. Dowdy, William A. Cliby, Bobbie S. Gostout, Sanjeev Kumar, Fabio Ghezzi, Francesco Multinu, Andrea Mariani

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Aim: The aim of the present study was to estimate the incisional recurrence (IR) rate after endometrial cancer (EC) staging surgery and analyze characteristics of affected patients. Patients and Methods: We retrospectively searched for patients with EC at 2 institutions and analyzed the occurrence of IR after open, laparoscopic, or robotic surgery. Additionally, a review of the literature was performed. Results: Out of 2,636 patients with EC, 1,732 (65.7%), 461 (17.5%), and 443 (16.8%) had open, laparoscopic, and robotic surgery, respectively. Only 3 patients (0.11%) had IR, all after open surgery. Additionally, 38 cases of IR were identified from the literature. Patients with non-isolated IR had worse overall survival than patients with isolated IR (p=0.04). Among this latter group, combined treatments may be associated with improved survival outcome. Conclusion: IR after EC surgery is rare and may occur after minimally-invasive or open operations. Combination of local and systemic treatments may provide favorable outcomes for patients with isolated IR.

Original languageEnglish
Pages (from-to)6097-6104
Number of pages8
JournalAnticancer Research
Volume35
Issue number11
Publication statusPublished - Nov 1 2015

Fingerprint

Endometrial Neoplasms
Recurrence
Robotics
Survival
Neoplasm Staging
Laparoscopy
Therapeutics

Keywords

  • Endometrial cancer
  • Incisional recurrence
  • Laparoscopy
  • Open surgery
  • Port site metastases

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Bogani, G., Dowdy, S. C., Cliby, W. A., Gostout, B. S., Kumar, S., Ghezzi, F., ... Mariani, A. (2015). Incisional recurrences after endometrial cancer surgery. Anticancer Research, 35(11), 6097-6104.

Incisional recurrences after endometrial cancer surgery. / Bogani, Giorgio; Dowdy, Sean C.; Cliby, William A.; Gostout, Bobbie S.; Kumar, Sanjeev; Ghezzi, Fabio; Multinu, Francesco; Mariani, Andrea.

In: Anticancer Research, Vol. 35, No. 11, 01.11.2015, p. 6097-6104.

Research output: Contribution to journalArticle

Bogani, G, Dowdy, SC, Cliby, WA, Gostout, BS, Kumar, S, Ghezzi, F, Multinu, F & Mariani, A 2015, 'Incisional recurrences after endometrial cancer surgery', Anticancer Research, vol. 35, no. 11, pp. 6097-6104.
Bogani G, Dowdy SC, Cliby WA, Gostout BS, Kumar S, Ghezzi F et al. Incisional recurrences after endometrial cancer surgery. Anticancer Research. 2015 Nov 1;35(11):6097-6104.
Bogani, Giorgio ; Dowdy, Sean C. ; Cliby, William A. ; Gostout, Bobbie S. ; Kumar, Sanjeev ; Ghezzi, Fabio ; Multinu, Francesco ; Mariani, Andrea. / Incisional recurrences after endometrial cancer surgery. In: Anticancer Research. 2015 ; Vol. 35, No. 11. pp. 6097-6104.
@article{6e67d1984229465d89c9128507b15d7e,
title = "Incisional recurrences after endometrial cancer surgery",
abstract = "Aim: The aim of the present study was to estimate the incisional recurrence (IR) rate after endometrial cancer (EC) staging surgery and analyze characteristics of affected patients. Patients and Methods: We retrospectively searched for patients with EC at 2 institutions and analyzed the occurrence of IR after open, laparoscopic, or robotic surgery. Additionally, a review of the literature was performed. Results: Out of 2,636 patients with EC, 1,732 (65.7{\%}), 461 (17.5{\%}), and 443 (16.8{\%}) had open, laparoscopic, and robotic surgery, respectively. Only 3 patients (0.11{\%}) had IR, all after open surgery. Additionally, 38 cases of IR were identified from the literature. Patients with non-isolated IR had worse overall survival than patients with isolated IR (p=0.04). Among this latter group, combined treatments may be associated with improved survival outcome. Conclusion: IR after EC surgery is rare and may occur after minimally-invasive or open operations. Combination of local and systemic treatments may provide favorable outcomes for patients with isolated IR.",
keywords = "Endometrial cancer, Incisional recurrence, Laparoscopy, Open surgery, Port site metastases",
author = "Giorgio Bogani and Dowdy, {Sean C.} and Cliby, {William A.} and Gostout, {Bobbie S.} and Sanjeev Kumar and Fabio Ghezzi and Francesco Multinu and Andrea Mariani",
year = "2015",
month = "11",
day = "1",
language = "English",
volume = "35",
pages = "6097--6104",
journal = "Anticancer Research",
issn = "0250-7005",
publisher = "International Institute of Anticancer Research",
number = "11",

}

TY - JOUR

T1 - Incisional recurrences after endometrial cancer surgery

AU - Bogani, Giorgio

AU - Dowdy, Sean C.

AU - Cliby, William A.

AU - Gostout, Bobbie S.

AU - Kumar, Sanjeev

AU - Ghezzi, Fabio

AU - Multinu, Francesco

AU - Mariani, Andrea

PY - 2015/11/1

Y1 - 2015/11/1

N2 - Aim: The aim of the present study was to estimate the incisional recurrence (IR) rate after endometrial cancer (EC) staging surgery and analyze characteristics of affected patients. Patients and Methods: We retrospectively searched for patients with EC at 2 institutions and analyzed the occurrence of IR after open, laparoscopic, or robotic surgery. Additionally, a review of the literature was performed. Results: Out of 2,636 patients with EC, 1,732 (65.7%), 461 (17.5%), and 443 (16.8%) had open, laparoscopic, and robotic surgery, respectively. Only 3 patients (0.11%) had IR, all after open surgery. Additionally, 38 cases of IR were identified from the literature. Patients with non-isolated IR had worse overall survival than patients with isolated IR (p=0.04). Among this latter group, combined treatments may be associated with improved survival outcome. Conclusion: IR after EC surgery is rare and may occur after minimally-invasive or open operations. Combination of local and systemic treatments may provide favorable outcomes for patients with isolated IR.

AB - Aim: The aim of the present study was to estimate the incisional recurrence (IR) rate after endometrial cancer (EC) staging surgery and analyze characteristics of affected patients. Patients and Methods: We retrospectively searched for patients with EC at 2 institutions and analyzed the occurrence of IR after open, laparoscopic, or robotic surgery. Additionally, a review of the literature was performed. Results: Out of 2,636 patients with EC, 1,732 (65.7%), 461 (17.5%), and 443 (16.8%) had open, laparoscopic, and robotic surgery, respectively. Only 3 patients (0.11%) had IR, all after open surgery. Additionally, 38 cases of IR were identified from the literature. Patients with non-isolated IR had worse overall survival than patients with isolated IR (p=0.04). Among this latter group, combined treatments may be associated with improved survival outcome. Conclusion: IR after EC surgery is rare and may occur after minimally-invasive or open operations. Combination of local and systemic treatments may provide favorable outcomes for patients with isolated IR.

KW - Endometrial cancer

KW - Incisional recurrence

KW - Laparoscopy

KW - Open surgery

KW - Port site metastases

UR - http://www.scopus.com/inward/record.url?scp=84946047928&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84946047928&partnerID=8YFLogxK

M3 - Article

C2 - 26504035

AN - SCOPUS:84946047928

VL - 35

SP - 6097

EP - 6104

JO - Anticancer Research

JF - Anticancer Research

SN - 0250-7005

IS - 11

ER -