Human one-way mixed lymphocyte culture induces a significant increase of EA(7S) rosette-forming cells, Using fractionation procedures, an increased number of Fc receptor-bearing cells in the T high-enriched populations was found from alloactivated lymphocytes compared with similar fractions obtained after autologous control cultures. Additional experiments showed a parallel increase of E-rosette-forming cells in the Fc receptor-enriched alloactivated fractions. The results indicate that an increase of TG lymphocytes occurs during in vitro alloactivation in man.
ASJC Scopus subject areas
- Immunology and Allergy