Increased CD10/TdT positive cells in the bone marrow of an infant with immune thrombocytopenia

L. M A Melillo, N. Cascavilla, P. Musto, M. M. Minervini, S. Ladogana, A. La Sala, M. Carotenuto

Research output: Contribution to journalArticlepeer-review

Abstract

We describe the case of an infant with immune thrombocytopenia whose bone marrow showed an increased percentage of CB10/TdT-positive lymphoid cells that resembled the onset of an acute lymphoproliferative disorder. Genotypic analysis of bone marrow, however, failed to reveal the malignant origin of these B cell precursors. After 8 months of follow-up, the child is alive and well, and shows a chronic form of ITP. Although a relation between this B cell proliferation and the onset of ITP cannot be excluded, it is important to consider this atypical pattern as a benign hematologic condition.

Original languageEnglish
Pages (from-to)177-179
Number of pages3
JournalHaematologica
Volume79
Issue number2
Publication statusPublished - 1994

Keywords

  • bone marrow
  • CD10/TdT positive lymphocytes
  • immune thrombocytopenia

ASJC Scopus subject areas

  • Hematology

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