Abstract
We describe the case of an infant with immune thrombocytopenia whose bone marrow showed an increased percentage of CB10/TdT-positive lymphoid cells that resembled the onset of an acute lymphoproliferative disorder. Genotypic analysis of bone marrow, however, failed to reveal the malignant origin of these B cell precursors. After 8 months of follow-up, the child is alive and well, and shows a chronic form of ITP. Although a relation between this B cell proliferation and the onset of ITP cannot be excluded, it is important to consider this atypical pattern as a benign hematologic condition.
Original language | English |
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Pages (from-to) | 177-179 |
Number of pages | 3 |
Journal | Haematologica |
Volume | 79 |
Issue number | 2 |
Publication status | Published - 1994 |
Keywords
- bone marrow
- CD10/TdT positive lymphocytes
- immune thrombocytopenia
ASJC Scopus subject areas
- Hematology