Increased coronary tone in exertional angina: The beneficial effects of calcium antagonists

Giuseppe Specchia, Diego Ardissino, Stefano Ghio, Paolo Barberis, Maria Luigia Colombo, Stefano De Servi

Research output: Contribution to journalArticlepeer-review

Abstract

Coronary vasoconstriction may play a relevant role in the pathogenesis of exercise-induced myocardial ischemia, not only in patients with Prinzmetal's angina, but also in patients with chronic stable angina. In these patients the use of calcium antagonists, namely, dihydropyridine derivatives, may be beneficial. Hyperventilation is a simple and sensitive test to discriminate patients with effort angina who will improve their exercise capacity after administration of these drugs.

Original languageEnglish
Pages (from-to)893-897
Number of pages5
JournalCardiovascular Drugs and Therapy
Volume4
Issue number5 Supplement
DOIs
Publication statusPublished - Sep 1990

Keywords

  • coronary vasoconstriction
  • exercise-induced angina
  • hyperventilation

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Cardiology and Cardiovascular Medicine

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