Increased neutrophil aggregability in coronary artery disease

G. Ricevuti, S. De Servi, A. Mazzone, L. Angoli, S. Ghio, G. Specchia

Research output: Contribution to journalArticlepeer-review


The purpose of this investigation was to study neutrophil (PMN) aggregation in the aorta and coronary sinus of 20 patients with angiographically documented coronary artery disease (group I) compared with eight patients with normal coronary arteries (group II). PMNs were separated from the other blood components and their aggregation response to Ca2+ ionophore A 23187 1 × 10-5 M (final concentration) was measured. Group I patients had higher aggregating activity in the coronary sinus than in the aorta (24·9±3·7 vs 18·7±3·4 average maximum ΔT, P

Original languageEnglish
Pages (from-to)814-818
Number of pages5
JournalEuropean Heart Journal
Issue number9
Publication statusPublished - 1990


  • Aggregation
  • Coronary artery disease
  • Neutrophil

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Physiology


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