Abstract
Objectives: The Global Cardiometabolic Risk Profile in Patients with hypertension disease survey investigated the cardiometabolic risk profile in adult outpatients with hypertension in Europe according to the control of blood pressure (BP) as defined in the European Society of Hypertension and of the European Society of Cardiology (ESH/ESC) guidelines. Methods: Data on BP control and cardiometabolic risk factors were collected for 3370 patients with hypertension in 12 European countries. Prevalence was analyzed according to BP status and ATP III criteria for metabolic syndrome. Results: BP was controlled (BP <140/90 mmHg for nondiabetic patients; BP <130/80 mmHg for diabetic patients) in 28.1% of patients. Patients with uncontrolled BP had significantly higher mean weight, BMI, waist circumference, fasting blood glucose, total cholesterol and triglycerides and high-density lipoprotein cholesterol levels were significantly lower (women only) compared with patients with controlled BP (P <0.05). The prevalence of metabolic syndrome and type 2 diabetes was also significantly higher in patients with uncontrolled BP compared with controlled BP (P <0.001) (metabolic syndrome: 66.5 versus 35.5%; diabetes 41.1 versus 9.8%, respectively). 95.3% of patients with both metabolic syndrome and type 2 diabetes had uncontrolled BP. In a multivariate analysis, diabetes and metabolic syndrome were found to be associated with a high risk of poor BP control: odds ratio, 2.56 (metabolic syndrome); 5.16 (diabetes). Conclusion: In this European study, fewer than one third of treated hypertensive patients had controlled BP. Metabolic syndrome and diabetes were important characteristics associated with poor BP control. Thus, more focus is needed on controlling hypertension in people with high cardiometabolic risk and diabetes.
| Original language | English |
|---|---|
| Pages (from-to) | 2064-2070 |
| Number of pages | 7 |
| Journal | Journal of Hypertension |
| Volume | 26 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Oct 2008 |
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Keywords
- blood pressure control
- cardiometabolic risk factors
- cardiovascular risk
- diabetes
- hypertension
- metabolic syndrome
ASJC Scopus subject areas
- Internal Medicine
- Physiology
- Cardiology and Cardiovascular Medicine
Cite this
Increased prevalence of metabolic syndrome in uncontrolled hypertension across Europe : The Global Cardiometabolic Risk Profile in Patients with hypertension disease survey. / Kjeldsen, Sverre E.; Naditch-Brule, Lisa; Perlini, Stefano; Zidek, Walter; Farsang, Csaba.
In: Journal of Hypertension, Vol. 26, No. 10, 10.2008, p. 2064-2070.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Increased prevalence of metabolic syndrome in uncontrolled hypertension across Europe
T2 - The Global Cardiometabolic Risk Profile in Patients with hypertension disease survey
AU - Kjeldsen, Sverre E.
AU - Naditch-Brule, Lisa
AU - Perlini, Stefano
AU - Zidek, Walter
AU - Farsang, Csaba
PY - 2008/10
Y1 - 2008/10
N2 - Objectives: The Global Cardiometabolic Risk Profile in Patients with hypertension disease survey investigated the cardiometabolic risk profile in adult outpatients with hypertension in Europe according to the control of blood pressure (BP) as defined in the European Society of Hypertension and of the European Society of Cardiology (ESH/ESC) guidelines. Methods: Data on BP control and cardiometabolic risk factors were collected for 3370 patients with hypertension in 12 European countries. Prevalence was analyzed according to BP status and ATP III criteria for metabolic syndrome. Results: BP was controlled (BP <140/90 mmHg for nondiabetic patients; BP <130/80 mmHg for diabetic patients) in 28.1% of patients. Patients with uncontrolled BP had significantly higher mean weight, BMI, waist circumference, fasting blood glucose, total cholesterol and triglycerides and high-density lipoprotein cholesterol levels were significantly lower (women only) compared with patients with controlled BP (P <0.05). The prevalence of metabolic syndrome and type 2 diabetes was also significantly higher in patients with uncontrolled BP compared with controlled BP (P <0.001) (metabolic syndrome: 66.5 versus 35.5%; diabetes 41.1 versus 9.8%, respectively). 95.3% of patients with both metabolic syndrome and type 2 diabetes had uncontrolled BP. In a multivariate analysis, diabetes and metabolic syndrome were found to be associated with a high risk of poor BP control: odds ratio, 2.56 (metabolic syndrome); 5.16 (diabetes). Conclusion: In this European study, fewer than one third of treated hypertensive patients had controlled BP. Metabolic syndrome and diabetes were important characteristics associated with poor BP control. Thus, more focus is needed on controlling hypertension in people with high cardiometabolic risk and diabetes.
AB - Objectives: The Global Cardiometabolic Risk Profile in Patients with hypertension disease survey investigated the cardiometabolic risk profile in adult outpatients with hypertension in Europe according to the control of blood pressure (BP) as defined in the European Society of Hypertension and of the European Society of Cardiology (ESH/ESC) guidelines. Methods: Data on BP control and cardiometabolic risk factors were collected for 3370 patients with hypertension in 12 European countries. Prevalence was analyzed according to BP status and ATP III criteria for metabolic syndrome. Results: BP was controlled (BP <140/90 mmHg for nondiabetic patients; BP <130/80 mmHg for diabetic patients) in 28.1% of patients. Patients with uncontrolled BP had significantly higher mean weight, BMI, waist circumference, fasting blood glucose, total cholesterol and triglycerides and high-density lipoprotein cholesterol levels were significantly lower (women only) compared with patients with controlled BP (P <0.05). The prevalence of metabolic syndrome and type 2 diabetes was also significantly higher in patients with uncontrolled BP compared with controlled BP (P <0.001) (metabolic syndrome: 66.5 versus 35.5%; diabetes 41.1 versus 9.8%, respectively). 95.3% of patients with both metabolic syndrome and type 2 diabetes had uncontrolled BP. In a multivariate analysis, diabetes and metabolic syndrome were found to be associated with a high risk of poor BP control: odds ratio, 2.56 (metabolic syndrome); 5.16 (diabetes). Conclusion: In this European study, fewer than one third of treated hypertensive patients had controlled BP. Metabolic syndrome and diabetes were important characteristics associated with poor BP control. Thus, more focus is needed on controlling hypertension in people with high cardiometabolic risk and diabetes.
KW - blood pressure control
KW - cardiometabolic risk factors
KW - cardiovascular risk
KW - diabetes
KW - hypertension
KW - metabolic syndrome
UR - http://www.scopus.com/inward/record.url?scp=58149116671&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=58149116671&partnerID=8YFLogxK
U2 - 10.1097/HJH.0b013e32830c45c3
DO - 10.1097/HJH.0b013e32830c45c3
M3 - Article
C2 - 18806632
AN - SCOPUS:58149116671
VL - 26
SP - 2064
EP - 2070
JO - Journal of Hypertension
JF - Journal of Hypertension
SN - 0263-6352
IS - 10
ER -