Abstract
Higher levels of soluble adhesion molecules have been found before the introduction of highly active antiretroviral therapy (HAART) in HIV-positive compared with HIV-negative patients. To evaluate the impact of HAART on endothelial function we measured the plasmatic concentrations of soluble adhesion molecules in 120 HIV-positive patients. Concentrations of P-selectin and fibrinolytic factors were significantly higher in HAART patients, whereas soluble intercellular adhesion molecule-1 did not differ significantly. HAART may induce an activation of endothelial function both directly and indirectly through lipid alterations.
Original language | English |
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Pages (from-to) | 765-768 |
Number of pages | 4 |
Journal | AIDS (London, England) |
Volume | 17 |
Issue number | 5 |
DOIs | |
Publication status | Published - Mar 28 2003 |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology