Abstract
In this study performed in rats, we measured extracellular lactate levels within different brain areas after a variety of stimuli using microdialysis. Experiments were performed using natural, physiological stimulation and experimental convulsive seizures. Generalized and limbic seizures produced a pronounced increase in lactic acid and a similar increase was obtained when the animals underwent olfactory stimulation. Increase in lactic acid occurred with site specificity and crucially relied on the quality of the stimulus.
Translated title of the contribution | Increases in extracellular lactate as an index of neuronal activity in awake freely moving animals |
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Original language | Italian |
Pages (from-to) | 233-235 |
Number of pages | 3 |
Journal | Bollettino - Lega Italiana contro l'Epilessia |
Issue number | 99 |
Publication status | Published - 1997 |
ASJC Scopus subject areas
- Clinical Neurology