Abstract
In this study performed in rats, we measured extracellular lactate levels within different brain areas after a variety of stimuli using microdialysis. Experiments were performed using natural, physiological stimulation and experimental convulsive seizures. Generalized and limbic seizures produced a pronounced increase in lactic acid and a similar increase was obtained when the animals underwent olfactory stimulation. Increase in lactic acid occurred with site specificity and crucially relied on the quality of the stimulus.
| Translated title of the contribution | Increases in extracellular lactate as an index of neuronal activity in awake freely moving animals |
|---|---|
| Original language | Italian |
| Pages (from-to) | 233-235 |
| Number of pages | 3 |
| Journal | Bollettino - Lega Italiana contro l'Epilessia |
| Issue number | 99 |
| Publication status | Published - 1997 |
ASJC Scopus subject areas
- Clinical Neurology