Abstract
From this retrospective single center analysis adults with acute lymphobalstic leukemia transplanted in ≥2nd CR from an HLA-identical sibling later than 1993 had a worse outcome. As the transplanted-related mortality improved by time, this result was essentially due to the increased relapse rate. The intensity of the pre-transplant salvage chemotherapy was identified as the main factor influencing the post-transplant relapse-risk.
| Original language | English |
|---|---|
| Pages (from-to) | 782-784 |
| Number of pages | 3 |
| Journal | Haematologica |
| Volume | 87 |
| Issue number | 7 |
| Publication status | Published - 2002 |
Fingerprint
Keywords
- Adult acute lymphoblastic leukemia
- Allogeneic stem cell transplantation
- Leukemia relapse
- Multi-drug resistance
ASJC Scopus subject areas
- Hematology
Cite this
Increasing risk of relapse after allogeneic stem cell transplant for adult acute lymphoblastic leukemia in ≥ 2nd complete remission induced by highly intensive chemotherapy. / Mengarelli, Andrea; Iori, Anna Paola; Cerretti, Raffaella; Cerilli, Lorenza; Romano, Atelda; Arcese, William.
In: Haematologica, Vol. 87, No. 7, 2002, p. 782-784.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Increasing risk of relapse after allogeneic stem cell transplant for adult acute lymphoblastic leukemia in ≥ 2nd complete remission induced by highly intensive chemotherapy
AU - Mengarelli, Andrea
AU - Iori, Anna Paola
AU - Cerretti, Raffaella
AU - Cerilli, Lorenza
AU - Romano, Atelda
AU - Arcese, William
PY - 2002
Y1 - 2002
N2 - From this retrospective single center analysis adults with acute lymphobalstic leukemia transplanted in ≥2nd CR from an HLA-identical sibling later than 1993 had a worse outcome. As the transplanted-related mortality improved by time, this result was essentially due to the increased relapse rate. The intensity of the pre-transplant salvage chemotherapy was identified as the main factor influencing the post-transplant relapse-risk.
AB - From this retrospective single center analysis adults with acute lymphobalstic leukemia transplanted in ≥2nd CR from an HLA-identical sibling later than 1993 had a worse outcome. As the transplanted-related mortality improved by time, this result was essentially due to the increased relapse rate. The intensity of the pre-transplant salvage chemotherapy was identified as the main factor influencing the post-transplant relapse-risk.
KW - Adult acute lymphoblastic leukemia
KW - Allogeneic stem cell transplantation
KW - Leukemia relapse
KW - Multi-drug resistance
UR - http://www.scopus.com/inward/record.url?scp=0036070536&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036070536&partnerID=8YFLogxK
M3 - Article
VL - 87
SP - 782
EP - 784
JO - Haematologica
JF - Haematologica
SN - 0390-6078
IS - 7
ER -