Abstract
From this retrospective single center analysis adults with acute lymphobalstic leukemia transplanted in ≥2nd CR from an HLA-identical sibling later than 1993 had a worse outcome. As the transplanted-related mortality improved by time, this result was essentially due to the increased relapse rate. The intensity of the pre-transplant salvage chemotherapy was identified as the main factor influencing the post-transplant relapse-risk.
| Original language | English |
|---|---|
| Pages (from-to) | 782-784 |
| Number of pages | 3 |
| Journal | Haematologica |
| Volume | 87 |
| Issue number | 7 |
| Publication status | Published - 2002 |
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Keywords
- Adult acute lymphoblastic leukemia
- Allogeneic stem cell transplantation
- Leukemia relapse
- Multi-drug resistance
ASJC Scopus subject areas
- Hematology
Cite this
Mengarelli, A., Iori, A. P., Cerretti, R., Cerilli, L., Romano, A., & Arcese, W. (2002). Increasing risk of relapse after allogeneic stem cell transplant for adult acute lymphoblastic leukemia in ≥ 2nd complete remission induced by highly intensive chemotherapy. Haematologica, 87(7), 782-784.