Increasing support by nasal high flow acutely modifies the ROX index in hypoxemic patients: A physiologic study

Tommaso Mauri, Eleonora Carlesso, Elena Spinelli, Cecilia Turrini, Francesca Dalla Corte, Riccarda Russo, Jean Damien Ricard, Antonio Pesenti, Oriol Roca, Giacomo Grasselli

Research output: Contribution to journalArticlepeer-review

Abstract

The ROX (Respiratory rate-OXygenation) index is an early predictor of failure of nasal high flow (NHF), with lower values indicating higher risk of intubation. We measured the ROX index at set flow rate of 30 and 60 l/min in 57 hypoxemic patients on NHF. Patients with increased ROX index values at higher flow (n = 40) showed worse baseline oxygenation, higher respiratory rate and lower ROX index in comparison to patients with unchanged or decreased ROX index values (n = 17). The ROX index variation between flows was correlated with the change in end expiratory lung volume. Set flow rate during NHF might impact the ROX index value.

Original languageEnglish
Pages (from-to)183-185
Number of pages3
JournalJournal of Critical Care
Volume53
DOIs
Publication statusPublished - Oct 1 2019

Keywords

  • Acute hypoxemic respiratory failure
  • Electrical impedance tomography
  • Monitoring
  • Nasal high flow

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

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