Incremental diagnostic value of dipyridamole echocardiography and exercise thallium 201 scintigraphy in the assessment of presence and extent of coronary artery disease

Vitantonio Di Bello, Enrico Gori, Calogero Riccardo Bellina, Oberdan Parodi, Nicola Molea, Gino Santoro, Giuliano Mariani, Umberto Conti, Enrico Magagnini, Paolo Marzullo, Luigi Talarico, Carmine Di Muro, Maria Francesca Romano, Romano Bianchi, Costantino Giusti

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The incremental diagnostic information of two noninvasive tests for the detection of coronary artery disease (CAD), dipyridamole echocardiography, and exercise201Tl myocardial scintigraphy was assessed in a series of 102 patients with ordered logistic regression and receiver-operating characteristic curves. Methods and Results: Patients were selected from those referred to our cardiovascular centers with the clinical suspicion of CAD. After clinical evaluation, all patients underwent both noninvasive tests during hospitalization 2 weeks before coronary arteriography. The coronary arteriogram was used as a gold standard: CAD was defined as the presence of one or more vessels with 50% or greater narrowing of the luminal diameter. Clinical data were 73.0%±5.7% accurate in the prediction of CAD. The addition of dipyridamole echocardiographic data to the clinical model yielded a diagnostic accuracy of 88.3%±4.3% (p

Original languageEnglish
Pages (from-to)372-381
Number of pages10
JournalJournal of Nuclear Cardiology
Volume1
Issue number4
DOIs
Publication statusPublished - Jul 1994

Keywords

  • coronary artery disease
  • dipyridamole echocardiography
  • thallium 201 scintigraphy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

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