Independent hypothalamic circuits for social and predator fear

Bianca A. Silva, Camilla Mattucci, Piotr Krzywkowski, Emanuele Murana, Anna Illarionova, Valery Grinevich, Newton S. Canteras, Davide Ragozzino, Cornelius T. Gross

Research output: Contribution to journalArticlepeer-review


The neural circuits mediating fear to naturalistic threats are poorly understood. We found that functionally independent populations of neurons in the ventromedial hypothalamus (VMH), a region that has been implicated in feeding, sex and aggression, are essential for predator and social fear in mice. Our results establish a critical role for VMH in fear and have implications for selective intervention in pathological fear in humans.

Original languageEnglish
Pages (from-to)1731-1733
Number of pages3
JournalNature Neuroscience
Issue number12
Publication statusPublished - 2013

ASJC Scopus subject areas

  • Neuroscience(all)


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