Independent prognostic value of fascin immunoreactivity in stage III-IV colonic adenocarcinoma

G. Puppa; P. Maisonneuve; A. Sonzogni; M. Masullo; A. Chiappa; M. Valerio; M. G. Zampino; I. Franceschetti; P. Capelli; M. Chilosi; F. Menestrina; G. Viale; G. Pelosi

doi:10.1038/sj.bjc.6603690

Independent prognostic value of fascin immunoreactivity in stage III-IV colonic adenocarcinoma

G. Puppa, P. Maisonneuve, A. Sonzogni, M. Masullo, A. Chiappa, M. Valerio, M. G. Zampino, I. Franceschetti, P. Capelli, M. Chilosi, F. Menestrina, G. Viale, G. Pelosi

Research output: Contribution to journal › Article › peer-review

Abstract

Fascin, an actin-bundling protein involved in cell motility, has been shown to be upregulated in several types of carcinomas. In this study, we investigated the expression of fascin in 228 advanced colonic adenocarcinoma patients with a long follow-up. Fascin expression was compared with several clinicopathologic parameters and survival. Overall, fascin immunoreactivity was detected in 162 (71%) tumours with a prevalence for right-sided tumours (P

Original language	English
Pages (from-to)	1118-1126
Number of pages	9
Journal	British Journal of Cancer
Volume	96
Issue number	7
DOIs	https://doi.org/10.1038/sj.bjc.6603690
Publication status	Published - Apr 10 2007

Keywords

Colorectal cancer
Fascin
Immunohistochemistry
Prognosis

ASJC Scopus subject areas

Cancer Research
Oncology

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Independent prognostic value of fascin immunoreactivity in stage III-IV colonic adenocarcinoma. / Puppa, G.; Maisonneuve, P.; Sonzogni, A.; Masullo, M.; Chiappa, A.; Valerio, M.; Zampino, M. G.; Franceschetti, I.; Capelli, P.; Chilosi, M.; Menestrina, F.; Viale, G.; Pelosi, G.

In: British Journal of Cancer, Vol. 96, No. 7, 10.04.2007, p. 1118-1126.

Research output: Contribution to journal › Article › peer-review

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AU - Valerio, M.

AU - Zampino, M. G.

AU - Franceschetti, I.

AU - Capelli, P.

AU - Chilosi, M.

AU - Menestrina, F.

AU - Viale, G.

AU - Pelosi, G.

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