Abstract
Fascin, an actin-bundling protein involved in cell motility, has been shown to be upregulated in several types of carcinomas. In this study, we investigated the expression of fascin in 228 advanced colonic adenocarcinoma patients with a long follow-up. Fascin expression was compared with several clinicopathologic parameters and survival. Overall, fascin immunoreactivity was detected in 162 (71%) tumours with a prevalence for right-sided tumours (P
Original language | English |
---|---|
Pages (from-to) | 1118-1126 |
Number of pages | 9 |
Journal | British Journal of Cancer |
Volume | 96 |
Issue number | 7 |
DOIs | |
Publication status | Published - Apr 10 2007 |
Keywords
- Colorectal cancer
- Fascin
- Immunohistochemistry
- Prognosis
ASJC Scopus subject areas
- Cancer Research
- Oncology