Abstract
Fascin, an actin-bundling protein involved in cell motility, has been shown to be upregulated in several types of carcinomas. In this study, we investigated the expression of fascin in 228 advanced colonic adenocarcinoma patients with a long follow-up. Fascin expression was compared with several clinicopathologic parameters and survival. Overall, fascin immunoreactivity was detected in 162 (71%) tumours with a prevalence for right-sided tumours (P
| Original language | English |
|---|---|
| Pages (from-to) | 1118-1126 |
| Number of pages | 9 |
| Journal | British Journal of Cancer |
| Volume | 96 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Apr 10 2007 |
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Keywords
- Colorectal cancer
- Fascin
- Immunohistochemistry
- Prognosis
ASJC Scopus subject areas
- Cancer Research
- Oncology
Cite this
Independent prognostic value of fascin immunoreactivity in stage III-IV colonic adenocarcinoma. / Puppa, G.; Maisonneuve, P.; Sonzogni, A.; Masullo, M.; Chiappa, A.; Valerio, M.; Zampino, M. G.; Franceschetti, I.; Capelli, P.; Chilosi, M.; Menestrina, F.; Viale, G.; Pelosi, G.
In: British Journal of Cancer, Vol. 96, No. 7, 10.04.2007, p. 1118-1126.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Independent prognostic value of fascin immunoreactivity in stage III-IV colonic adenocarcinoma
AU - Puppa, G.
AU - Maisonneuve, P.
AU - Sonzogni, A.
AU - Masullo, M.
AU - Chiappa, A.
AU - Valerio, M.
AU - Zampino, M. G.
AU - Franceschetti, I.
AU - Capelli, P.
AU - Chilosi, M.
AU - Menestrina, F.
AU - Viale, G.
AU - Pelosi, G.
PY - 2007/4/10
Y1 - 2007/4/10
N2 - Fascin, an actin-bundling protein involved in cell motility, has been shown to be upregulated in several types of carcinomas. In this study, we investigated the expression of fascin in 228 advanced colonic adenocarcinoma patients with a long follow-up. Fascin expression was compared with several clinicopathologic parameters and survival. Overall, fascin immunoreactivity was detected in 162 (71%) tumours with a prevalence for right-sided tumours (P
AB - Fascin, an actin-bundling protein involved in cell motility, has been shown to be upregulated in several types of carcinomas. In this study, we investigated the expression of fascin in 228 advanced colonic adenocarcinoma patients with a long follow-up. Fascin expression was compared with several clinicopathologic parameters and survival. Overall, fascin immunoreactivity was detected in 162 (71%) tumours with a prevalence for right-sided tumours (P
KW - Colorectal cancer
KW - Fascin
KW - Immunohistochemistry
KW - Prognosis
UR - http://www.scopus.com/inward/record.url?scp=34247266530&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34247266530&partnerID=8YFLogxK
U2 - 10.1038/sj.bjc.6603690
DO - 10.1038/sj.bjc.6603690
M3 - Article
C2 - 17375048
AN - SCOPUS:34247266530
VL - 96
SP - 1118
EP - 1126
JO - British Journal of Cancer
JF - British Journal of Cancer
SN - 0007-0920
IS - 7
ER -