Independent prognostic value of tumour diameter and tumour necrosis in upper urinary tract urothelial carcinoma

Giuseppe Simone; Rocco Papalia; Andrea Loreto; Costantino Leonardo; Steno Sentinelli; Michele Gallucci

doi:10.1111/j.1464-410X.2008.08134.x

Independent prognostic value of tumour diameter and tumour necrosis in upper urinary tract urothelial carcinoma

Giuseppe Simone, Rocco Papalia, Andrea Loreto, Costantino Leonardo, Steno Sentinelli, Michele Gallucci

Istituto Regina Elena

Research output: Contribution to journal › Article › peer-review

Abstract

Objective To identify significant prognostic indicators of upper urinary tract (UUT) urothelial carcinoma (UC) and to assess a risk stratification of patients. Patients and methods We retrospectively analysed data from 162 patients with non-metastatic UC primarily occurring in UUT treated with open nephroureterectomy. Variables assessed included age, gender, pT, tumour grade, tumour necrosis extension, pN, tumour location, multifocal location, tumour diameter, and subsequent development of a bladder tumour. Tumour necrosis was measured using commercial software (Eureka interface system, version 4.0.22, HESP technology, Menarini Diagnostics, Italy) and was classified as none, focal (

Original language	English
Pages (from-to)	1052-1057
Number of pages	6
Journal	BJU International
Volume	103
Issue number	8
DOIs	https://doi.org/10.1111/j.1464-410X.2008.08134.x
Publication status	Published - Apr 2009

Keywords

Necrosis
Nephroureterectomy
Transitional cell carcinoma
Tumour diameter
Upper urinary tract
Urothelial carcinoma

ASJC Scopus subject areas

Urology

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title = "Independent prognostic value of tumour diameter and tumour necrosis in upper urinary tract urothelial carcinoma",

abstract = "Objective To identify significant prognostic indicators of upper urinary tract (UUT) urothelial carcinoma (UC) and to assess a risk stratification of patients. Patients and methods We retrospectively analysed data from 162 patients with non-metastatic UC primarily occurring in UUT treated with open nephroureterectomy. Variables assessed included age, gender, pT, tumour grade, tumour necrosis extension, pN, tumour location, multifocal location, tumour diameter, and subsequent development of a bladder tumour. Tumour necrosis was measured using commercial software (Eureka interface system, version 4.0.22, HESP technology, Menarini Diagnostics, Italy) and was classified as none, focal (",

keywords = "Necrosis, Nephroureterectomy, Transitional cell carcinoma, Tumour diameter, Upper urinary tract, Urothelial carcinoma",

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AU - Simone, Giuseppe

AU - Papalia, Rocco

AU - Loreto, Andrea

AU - Leonardo, Costantino

AU - Sentinelli, Steno

AU - Gallucci, Michele

PY - 2009/4

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KW - Urothelial carcinoma

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