Indexes from a parametric model of the interactions between heart period and arterial pressure variabilities

G. Baselli, S. Cerutti, F. Badilini, L. Biancardi, A. Porta, M. Pagani, F. Lombardi, O. Rimoldi, R. Furlan, A. Malliani

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A linear model for the evaluation of causal interactions between heart period (HP) and systolic arterial pressure (SAP) variabilities was applied to experimental data from conscious dogs and clinical data from mild hypertensive subjects. The structure of the model is designed in order to identify the source of low frequency (LF) spontaneous oscillations and the pathways conveying respiratory effects on the variabilities at high frequency (HF); in the meanwhile mechanical as well as baroreceptive mechanisms are evaluated. Different mechanisms coexist in the generation of both rhythms. LF is enhanced by arterial pressure (AP) regulation, but different sources affect the sinus node during coronary artery occlusion (CAO). A respiration to HP pathway is prevalent in dogs, while a respiration to SAP pathway is important in humans and is enhanced in dogs during sympathetic stimuli.

Original languageEnglish
Title of host publicationProceedings of the Annual Conference on Engineering in Medicine and Biology
PublisherPubl by IEEE
Pages2071-2072
Number of pages2
Volume13
Editionpt 5
ISBN (Print)0780302168
Publication statusPublished - 1991
EventProceedings of the 13th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Orlando, FL, USA
Duration: Oct 31 1991Nov 3 1991

Other

OtherProceedings of the 13th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CityOrlando, FL, USA
Period10/31/9111/3/91

ASJC Scopus subject areas

  • Bioengineering

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