Indications of anticonvulsant plasma levels monitoring in medical and surgical treatment of epilepsy

G. P. Cabrini, V. A. Sironi, F. Marossero, A. Baruzzi

Research output: Contribution to journalArticle

Abstract

The results of long term (19-21 mth) intensive anticonvulsant plasma levels monitoring in 2 patients with partial complex epilepsy resistant to therapy are reported. In the first case the qualitative and quantitative therapeutic adjustment based on the monitoring data caused the disappearance of the seizures. In the second case, in which a right mid-temporal calcification (abscess) was demonstrated by CT-scan, the attacks were not controlled by different drugs. The patient became seizure-free after a right temporal lobectomy. The importance of long term anticonvulsant plasma levels monitoring in partial complex epilepsies unresponsive to pharmacological therapy is discussed in detail in view of possible surgical treatment.

Original languageEnglish
Pages (from-to)29-36
Number of pages8
JournalJournal of Neurosurgical Sciences
Volume23
Issue number1
Publication statusPublished - 1979

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Anticonvulsants
Epilepsy
Complex Partial Epilepsy
Seizures
Therapeutics
Abscess
Pharmacology
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Indications of anticonvulsant plasma levels monitoring in medical and surgical treatment of epilepsy. / Cabrini, G. P.; Sironi, V. A.; Marossero, F.; Baruzzi, A.

In: Journal of Neurosurgical Sciences, Vol. 23, No. 1, 1979, p. 29-36.

Research output: Contribution to journalArticle

Cabrini, GP, Sironi, VA, Marossero, F & Baruzzi, A 1979, 'Indications of anticonvulsant plasma levels monitoring in medical and surgical treatment of epilepsy', Journal of Neurosurgical Sciences, vol. 23, no. 1, pp. 29-36.
Cabrini, G. P. ; Sironi, V. A. ; Marossero, F. ; Baruzzi, A. / Indications of anticonvulsant plasma levels monitoring in medical and surgical treatment of epilepsy. In: Journal of Neurosurgical Sciences. 1979 ; Vol. 23, No. 1. pp. 29-36.
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