Indications to upper gastrointestinal endoscopy in children with dyspepsia

G. Guariso, A. Meneghel, L. Visonà Dalla Pozza, C. Romano, L. Dall'Oglio, G. Lombardi, S. Conte, M. Calacoci, A. Campanozzi, C. Nichetti, S. Piovan, L. Zancan, P. Facchin

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Objectives: The objective of the study was to ascertain the appropriateness of indications for upper gastrointestinal (UGI) endoscopy in children with dyspepsia. Methods: We used the RAND/University of California at Los Angeles method to investigate the appropriateness of the opinions of a panel of experts. The panel judged 2304 theoretical patient scenarios defined by a combination of demographic and clinical variables. Descriptive and multivariate logistic regression analyses were performed. Results: The panel rated UGI endoscopy as appropriate in 27.2% of cases, inappropriate in 14.3%, and dubious in 58.5%. Disagreement emerged for 21% of cases. UGI endoscopy was considered increasingly appropriate in cases with a positive family history of peptic ulcer and/or Helicobacter pylori infection (odds ratio [OR] 8.518, P <0.0001), when dyspepsia interfered with activities of daily living ("sleep" OR 7.540, P <0.0001; "normal activities" OR 5.725, P <0.0001), and when patients were older than 10 years ("≤10 years" OR 0.310, P <0.0001) the longer the duration ("0-2 months" OR 0.002, P <0.0001; "3-5 months" OR 0.059, P <0.0001; "6-11 months" OR 0.516, P = 0.0005) and the greater the severity ("mild" OR 0.002, P <0.0001; "moderate" OR 0.013, P <0.0001) of their dyspeptic symptoms. Conclusions: UGI endoscopy is not appropriate for all children with dyspeptic symptoms, but only for cases with a family history of peptic ulcer and/or Helicobacter pylori infection, older than 10 years of age, with symptoms persisting for more than 6 months and severe enough to affect activities of daily living.

Original languageEnglish
Pages (from-to)493-499
Number of pages7
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume50
Issue number5
DOIs
Publication statusPublished - May 2010

Fingerprint

Gastrointestinal Endoscopy
Dyspepsia
Odds Ratio
Helicobacter Infections
Activities of Daily Living
Peptic Ulcer
Helicobacter pylori
Los Angeles
Sleep
Logistic Models
Regression Analysis
Demography

Keywords

  • Dyspepsia
  • Pediatric endoscopy
  • Pediatric gastrointestinal disease
  • Upper gastrointestinal endoscopy

ASJC Scopus subject areas

  • Gastroenterology
  • Pediatrics, Perinatology, and Child Health

Cite this

Indications to upper gastrointestinal endoscopy in children with dyspepsia. / Guariso, G.; Meneghel, A.; Pozza, L. Visonà Dalla; Romano, C.; Dall'Oglio, L.; Lombardi, G.; Conte, S.; Calacoci, M.; Campanozzi, A.; Nichetti, C.; Piovan, S.; Zancan, L.; Facchin, P.

In: Journal of Pediatric Gastroenterology and Nutrition, Vol. 50, No. 5, 05.2010, p. 493-499.

Research output: Contribution to journalArticle

Guariso, G, Meneghel, A, Pozza, LVD, Romano, C, Dall'Oglio, L, Lombardi, G, Conte, S, Calacoci, M, Campanozzi, A, Nichetti, C, Piovan, S, Zancan, L & Facchin, P 2010, 'Indications to upper gastrointestinal endoscopy in children with dyspepsia', Journal of Pediatric Gastroenterology and Nutrition, vol. 50, no. 5, pp. 493-499. https://doi.org/10.1097/MPG.0b013e3181bb3362
Guariso, G. ; Meneghel, A. ; Pozza, L. Visonà Dalla ; Romano, C. ; Dall'Oglio, L. ; Lombardi, G. ; Conte, S. ; Calacoci, M. ; Campanozzi, A. ; Nichetti, C. ; Piovan, S. ; Zancan, L. ; Facchin, P. / Indications to upper gastrointestinal endoscopy in children with dyspepsia. In: Journal of Pediatric Gastroenterology and Nutrition. 2010 ; Vol. 50, No. 5. pp. 493-499.
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AU - Meneghel, A.

AU - Pozza, L. Visonà Dalla

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AU - Dall'Oglio, L.

AU - Lombardi, G.

AU - Conte, S.

AU - Calacoci, M.

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