Indocyanine green angiography (icga) follow-up of plaque choroidal neovascularization in age-related macular degeneration

Purpose. To evaluate natural evolution of the plaque-CNV in Age Related Macular Degeneration studied by ICGA. Methods. A retrospective study of the ICGA of 37 consecutive eyes affected by ARMD which revealed occult CNV at Fluorescein Angiography was performed. The plaque area, revealed by ICGA as a macular area of well-defined hyperfluorescence, was measured at the initial and final control with the IMAGEnet 1024 area measurement tool by two observers (A-B). Results. Mean (±SD) follow-up was 11.86 (±8.04) months. Initial and final mean (±SD) visual acuity were 0.42 (±0.22) and 0.31 (±0.23), respectively. Initial mean (±SD) size was 6.29 mm' (±3.67) (ob.A) and 7.05 mm2 (±4.00) (ob.B). The final mean (±SD) size was 9.83 mm2 (±6.52) (ob.A), and 10.47 mm2 (±6.68) (ob.B). Mean size increment was 63.02% (ob.A) and 60.99% (ob.B). Conclusions. This study shows that plaque CNV may modify their typical angiographie ICGA patterns, showing an increasing in size, with no statistic correlation with the visual acuity decrease. This supports the current hypothesis that plaque CNV can be considered a type of CNV with little evolutive characteristics.