Indocyanine green angiography pattern of congenital grouped albinotic retinal pigment epithelial spots

Battaglia Parodi Maurizio, Iacono Pierluigi

Research output: Contribution to journalArticlepeer-review

Abstract

Congenital grouped albinotic retinal pigment epithelial spots (CGARPES) is a rare retinal pigment epithelium disease with multiple, white spots, generally involving the peripheral retina, with variable angiographic pattern. A 46-year-old male affected by CGARPES underwent fluorescein angiography and indocyanine green videoangiography. Fluorescein angiography demonstrated an early hyperfluorescence of the spots. A peculiar pattern was revealed by indocyanine green videoangiography. Indeed, during the early phases the spots were either not detectable on the choroidal background, or presented slightly hypofluorescent, whereas during the intermediate and the late phases some spots became progressively hyperfluorecent. The angiographic behavior on indocyanine green may be explained considering a gradual staining of the lesions, with a progressive binding between the indocyanine green molecule and the abnormal retinal pigment epithelium material.

Original languageEnglish
Pages (from-to)114-116
Number of pages3
JournalSeminars in Ophthalmology
Volume19
Issue number3-4
DOIs
Publication statusPublished - Sep 2004

Keywords

  • Congenital grouped albinotic retinal pigment epithelial spots
  • Fluorescein angiography
  • Indocyanine green angiography

ASJC Scopus subject areas

  • Ophthalmology

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