Abstract
Sputum induction can be used as a non-invasive technique to investigate airway inflammation in asthma and COPD. We reported the case of a 68 year old man with COPD, stage III GOLD, that underwent sputum induction during two exacerbation episodes. The first cell count showed a typical sputum neutrophilia, whereas the second showedsputum eosinophilia. On the basis of sputum cellularity, we decided to treat the first episode with a course of antibiotics and the second exacerbation with a course of antibiotics and oral steroids. The patient showed improvement in both cases, obtaining clinical stabilisation. The induced sputum cell count could be a useful technique in a clinical setting to evaluate the cellular characteristics of airway inflammation during COPD exacerbation and modulate the antinflammatory therapy.
| Original language | English |
|---|---|
| Pages (from-to) | 23-25 |
| Number of pages | 3 |
| Journal | Monaldi Archives for Chest Disease - Cardiac Series |
| Volume | 77 |
| Issue number | 1 |
| Publication status | Published - Mar 2012 |
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Keywords
- Airway inflammation
- COPD
- Induced sputum
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
Cite this
Induced sputum in the management of COPD : Clinical implications. / Zanini, Andrea; Della Patrona, S.; Facchini, A. L.; Spanevello, A.
In: Monaldi Archives for Chest Disease - Cardiac Series, Vol. 77, No. 1, 03.2012, p. 23-25.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Induced sputum in the management of COPD
T2 - Clinical implications
AU - Zanini, Andrea
AU - Della Patrona, S.
AU - Facchini, A. L.
AU - Spanevello, A.
PY - 2012/3
Y1 - 2012/3
N2 - Sputum induction can be used as a non-invasive technique to investigate airway inflammation in asthma and COPD. We reported the case of a 68 year old man with COPD, stage III GOLD, that underwent sputum induction during two exacerbation episodes. The first cell count showed a typical sputum neutrophilia, whereas the second showedsputum eosinophilia. On the basis of sputum cellularity, we decided to treat the first episode with a course of antibiotics and the second exacerbation with a course of antibiotics and oral steroids. The patient showed improvement in both cases, obtaining clinical stabilisation. The induced sputum cell count could be a useful technique in a clinical setting to evaluate the cellular characteristics of airway inflammation during COPD exacerbation and modulate the antinflammatory therapy.
AB - Sputum induction can be used as a non-invasive technique to investigate airway inflammation in asthma and COPD. We reported the case of a 68 year old man with COPD, stage III GOLD, that underwent sputum induction during two exacerbation episodes. The first cell count showed a typical sputum neutrophilia, whereas the second showedsputum eosinophilia. On the basis of sputum cellularity, we decided to treat the first episode with a course of antibiotics and the second exacerbation with a course of antibiotics and oral steroids. The patient showed improvement in both cases, obtaining clinical stabilisation. The induced sputum cell count could be a useful technique in a clinical setting to evaluate the cellular characteristics of airway inflammation during COPD exacerbation and modulate the antinflammatory therapy.
KW - Airway inflammation
KW - COPD
KW - Induced sputum
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UR - http://www.scopus.com/inward/citedby.url?scp=84861117794&partnerID=8YFLogxK
M3 - Article
C2 - 22662642
AN - SCOPUS:84861117794
VL - 77
SP - 23
EP - 25
JO - Monaldi Archives for Chest Disease
JF - Monaldi Archives for Chest Disease
SN - 1122-0643
IS - 1
ER -