Induction of fos expression by activity in the spinal rhythm generator for scratching

I. Barajon, J. P. Gossard, H. Hultborn

Research output: Contribution to journalArticlepeer-review


Fos expression was evaluated immunohistochemically in L7-S1 spinal segments after inducing fictive scratching in paralysed, unanaesthetized, decerebrate cats. The activity was induced by cutaneous stimulation of the pinna on one side and recorded from peripheral nerves. A cumulative duration of scratching of 60 to 90 min was effective in inducing fos expression. Most Fos-positive neurones were found in the dorsolateral part of the ventral horn and in the intermediate region of the spinal cord on the scratching side. In sham-operated animals the finding of Fos-positive neurones in these areas was very rare.

Original languageEnglish
Pages (from-to)168-172
Number of pages5
JournalBrain Research
Issue number1
Publication statusPublished - Aug 14 1992


  • C-fos
  • Cats
  • Immunohistochemistry
  • Interneuron
  • Rhythmic activity
  • Scratching
  • Spinal cord

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)


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