Infectious agents and lymphoma development: Molecular and clinical aspects

A. J M Ferreri, I. Ernberg, C. Copie-Bergman

Research output: Contribution to journalArticle

Abstract

Ferreri AJM, Ernberg I, Copie-Bergman C (San Raffaele Scientific Institute, Milan, Italy; Karolinska Institute, Stockholm, Sweden; and Université Paris, Créteil, France). Infectious agents and lymphoma development: molecular and clinical aspects (Review). J Intern Med 2009; 265: 421-438. This review is focused on the role of infectious agents in the development of some lymphoma entities. Associations involving bacterial infections mostly regard marginal zone B-cell lymphomas of mucosa-associated lymphoid tissue (MALT)-type. Some paradigmatic examples of these associations include the Helicobacter pylori-related gastric MALT lymphoma and the more recently reported links between Chlamydophila psittaci and ocular adnexal MALT lymphomas and Borrelia burgdorferi and cutaneous MALT lymphomas. The well-documented association between Epstein-Barr virus infection and related lymphoproliferative disorders are analysed as an example of lymphotropic virus with tumourigenic activity. Molecular, biological and clinical features as well as therapeutic implications of these associations are analysed and future perspectives in this field are discussed.

Original languageEnglish
Pages (from-to)421-438
Number of pages18
JournalJournal of Internal Medicine
Volume265
Issue number4
DOIs
Publication statusPublished - Apr 2009

Fingerprint

Marginal Zone B-Cell Lymphoma
Lymphoma
Chlamydophila psittaci
Borrelia burgdorferi
Epstein-Barr Virus Infections
Lymphoproliferative Disorders
Paris
Gastric Mucosa
Bacterial Infections
Sweden
Helicobacter pylori
Italy
France
Viruses
Skin

Keywords

  • Borrelia
  • Chlamydia psittaci
  • Epstein-Barr virus
  • Helicobacter pylori
  • Hodgkin lymphoma
  • Lymphomagenesis
  • MALT-type lymphoma

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Infectious agents and lymphoma development : Molecular and clinical aspects. / Ferreri, A. J M; Ernberg, I.; Copie-Bergman, C.

In: Journal of Internal Medicine, Vol. 265, No. 4, 04.2009, p. 421-438.

Research output: Contribution to journalArticle

Ferreri, A. J M ; Ernberg, I. ; Copie-Bergman, C. / Infectious agents and lymphoma development : Molecular and clinical aspects. In: Journal of Internal Medicine. 2009 ; Vol. 265, No. 4. pp. 421-438.
@article{73967ab0f399452c845581a4f1216064,
title = "Infectious agents and lymphoma development: Molecular and clinical aspects",
abstract = "Ferreri AJM, Ernberg I, Copie-Bergman C (San Raffaele Scientific Institute, Milan, Italy; Karolinska Institute, Stockholm, Sweden; and Universit{\'e} Paris, Cr{\'e}teil, France). Infectious agents and lymphoma development: molecular and clinical aspects (Review). J Intern Med 2009; 265: 421-438. This review is focused on the role of infectious agents in the development of some lymphoma entities. Associations involving bacterial infections mostly regard marginal zone B-cell lymphomas of mucosa-associated lymphoid tissue (MALT)-type. Some paradigmatic examples of these associations include the Helicobacter pylori-related gastric MALT lymphoma and the more recently reported links between Chlamydophila psittaci and ocular adnexal MALT lymphomas and Borrelia burgdorferi and cutaneous MALT lymphomas. The well-documented association between Epstein-Barr virus infection and related lymphoproliferative disorders are analysed as an example of lymphotropic virus with tumourigenic activity. Molecular, biological and clinical features as well as therapeutic implications of these associations are analysed and future perspectives in this field are discussed.",
keywords = "Borrelia, Chlamydia psittaci, Epstein-Barr virus, Helicobacter pylori, Hodgkin lymphoma, Lymphomagenesis, MALT-type lymphoma",
author = "Ferreri, {A. J M} and I. Ernberg and C. Copie-Bergman",
year = "2009",
month = "4",
doi = "10.1111/j.1365-2796.2009.02083.x",
language = "English",
volume = "265",
pages = "421--438",
journal = "Journal of Internal Medicine",
issn = "0954-6820",
publisher = "Wiley-Blackwell",
number = "4",

}

TY - JOUR

T1 - Infectious agents and lymphoma development

T2 - Molecular and clinical aspects

AU - Ferreri, A. J M

AU - Ernberg, I.

AU - Copie-Bergman, C.

PY - 2009/4

Y1 - 2009/4

N2 - Ferreri AJM, Ernberg I, Copie-Bergman C (San Raffaele Scientific Institute, Milan, Italy; Karolinska Institute, Stockholm, Sweden; and Université Paris, Créteil, France). Infectious agents and lymphoma development: molecular and clinical aspects (Review). J Intern Med 2009; 265: 421-438. This review is focused on the role of infectious agents in the development of some lymphoma entities. Associations involving bacterial infections mostly regard marginal zone B-cell lymphomas of mucosa-associated lymphoid tissue (MALT)-type. Some paradigmatic examples of these associations include the Helicobacter pylori-related gastric MALT lymphoma and the more recently reported links between Chlamydophila psittaci and ocular adnexal MALT lymphomas and Borrelia burgdorferi and cutaneous MALT lymphomas. The well-documented association between Epstein-Barr virus infection and related lymphoproliferative disorders are analysed as an example of lymphotropic virus with tumourigenic activity. Molecular, biological and clinical features as well as therapeutic implications of these associations are analysed and future perspectives in this field are discussed.

AB - Ferreri AJM, Ernberg I, Copie-Bergman C (San Raffaele Scientific Institute, Milan, Italy; Karolinska Institute, Stockholm, Sweden; and Université Paris, Créteil, France). Infectious agents and lymphoma development: molecular and clinical aspects (Review). J Intern Med 2009; 265: 421-438. This review is focused on the role of infectious agents in the development of some lymphoma entities. Associations involving bacterial infections mostly regard marginal zone B-cell lymphomas of mucosa-associated lymphoid tissue (MALT)-type. Some paradigmatic examples of these associations include the Helicobacter pylori-related gastric MALT lymphoma and the more recently reported links between Chlamydophila psittaci and ocular adnexal MALT lymphomas and Borrelia burgdorferi and cutaneous MALT lymphomas. The well-documented association between Epstein-Barr virus infection and related lymphoproliferative disorders are analysed as an example of lymphotropic virus with tumourigenic activity. Molecular, biological and clinical features as well as therapeutic implications of these associations are analysed and future perspectives in this field are discussed.

KW - Borrelia

KW - Chlamydia psittaci

KW - Epstein-Barr virus

KW - Helicobacter pylori

KW - Hodgkin lymphoma

KW - Lymphomagenesis

KW - MALT-type lymphoma

UR - http://www.scopus.com/inward/record.url?scp=61849140711&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=61849140711&partnerID=8YFLogxK

U2 - 10.1111/j.1365-2796.2009.02083.x

DO - 10.1111/j.1365-2796.2009.02083.x

M3 - Article

C2 - 19298458

AN - SCOPUS:61849140711

VL - 265

SP - 421

EP - 438

JO - Journal of Internal Medicine

JF - Journal of Internal Medicine

SN - 0954-6820

IS - 4

ER -