RIACUTIZZAZIONI DELLE BRONCOPNEUMOPATIE CRONICHE. UTILITA DEGLI IMMUNOMODULANTI

Translated title of the contribution: Infectious exacerbations of chronic pulmonary diseases. Therapeutic effectiveness of immunomodulants

M. P. Foschino Barbaro, O. Resta, A. Cassano, A. Altieri, P. Guido, A. Piti, E. Gramiccioni

Research output: Contribution to journalArticle

Abstract

The aim of this study was to evaluate the therapeutic effectiveness and safety of an association of membranous proteoglycans of Klebsiella pneumoniae and bacterial ribosomes of Klebsiella pneumoniae, Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae in patients suffering from recurrent respiratory infections. We have evaluated, in double blind randomized versus placebo study, 64 subjects affected by chronic bronchitis, with age ranging between 27 and 70 years, of both sexes. The drug was administered according to the following protocol: 1 tablet daily for 4 days in a week for 3 weeks and 1 tablet daily for 4 days in a month for 5 months. A significant reduction in infectious recurrences was obtained in all patients treated with the active drug. Our results suggest that the association of bacterial ribosomes and membranous proteoglycans of Klebsiella pneumoniae is effective in reducing recurrent respiratory infections.

Translated title of the contributionInfectious exacerbations of chronic pulmonary diseases. Therapeutic effectiveness of immunomodulants
Original languageItalian
Pages (from-to)39-44
Number of pages6
JournalMinerva Pneumologica
Volume34
Issue number2
Publication statusPublished - 1995

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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  • Cite this

    Foschino Barbaro, M. P., Resta, O., Cassano, A., Altieri, A., Guido, P., Piti, A., & Gramiccioni, E. (1995). RIACUTIZZAZIONI DELLE BRONCOPNEUMOPATIE CRONICHE. UTILITA DEGLI IMMUNOMODULANTI. Minerva Pneumologica, 34(2), 39-44.