Diagnostica immunoenzimatica della mononucleosi infettiva con test rapido

Translated title of the contribution: Infectious mononucleosis: Immunoenzymatic diagnosis with rapid test

Giorgio Tamaro, Michela Donato, Sergio Parco

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Objective: To establish if the determination of specific antigens against Epstein-Barr virus (EBV), by the commercial immunoenzymatic tests (VCA), may be a useful diagnostic and prognostic tool with a higher sensibility and specificity in respect to rapid diagnostic methods with heterophylous antibodies (MNI) is the aim of this paper. Methods: 163 serum samples of paediatric patients, subdivided in eight groups have been studied. Results: This method has a good specificity (92.6% in the first group and 84.8% in the second group) in patients without or with a past history of EBV infection (positive attended value). While the sensibility is only of 61.8%. in patients with active disease (the third group). Discussion: VCA tests hould be used in case of a doubtful diagnosis or for a latent or in evolution disease.

Translated title of the contributionInfectious mononucleosis: Immunoenzymatic diagnosis with rapid test
Original languageItalian
Title of host publicationQuaderni ACP
Pages56-58
Number of pages3
Volume15
Edition2
Publication statusPublished - Mar 2008

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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  • Cite this

    Tamaro, G., Donato, M., & Parco, S. (2008). Diagnostica immunoenzimatica della mononucleosi infettiva con test rapido. In Quaderni ACP (2 ed., Vol. 15, pp. 56-58)