Objective: To establish if the determination of specific antigens against Epstein-Barr virus (EBV), by the commercial immunoenzymatic tests (VCA), may be a useful diagnostic and prognostic tool with a higher sensibility and specificity in respect to rapid diagnostic methods with heterophylous antibodies (MNI) is the aim of this paper. Methods: 163 serum samples of paediatric patients, subdivided in eight groups have been studied. Results: This method has a good specificity (92.6% in the first group and 84.8% in the second group) in patients without or with a past history of EBV infection (positive attended value). While the sensibility is only of 61.8%. in patients with active disease (the third group). Discussion: VCA tests hould be used in case of a doubtful diagnosis or for a latent or in evolution disease.
|Translated title of the contribution||Infectious mononucleosis: Immunoenzymatic diagnosis with rapid test|
|Title of host publication||Quaderni ACP|
|Number of pages||3|
|Publication status||Published - Mar 2008|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health