TY - GEN
T1 - Infiltration of tumours by macrophages and dendritic cells
T2 - Tumour-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
AU - Mantovani, Alberto
AU - Sozzani, Silvano
AU - Locati, Massimo
AU - Schioppa, Tiziana
AU - Saccani, Alessandra
AU - Allavena, Paola
AU - Sica, Antonio
PY - 2004
Y1 - 2004
N2 - Macrophages and dendritic cells infiltrate tumours. In the tumour microenvironment, mononuclear phagocytes acquire properties of polarized M2 (or alternatively activated) macrophages. These functionally polarized cells, and similarly oriented or immature dendritic cells present in tumours, play a key role in subversion of adaptive immunity and in inflammatory circuits which promote tumour growth and progression.
AB - Macrophages and dendritic cells infiltrate tumours. In the tumour microenvironment, mononuclear phagocytes acquire properties of polarized M2 (or alternatively activated) macrophages. These functionally polarized cells, and similarly oriented or immature dendritic cells present in tumours, play a key role in subversion of adaptive immunity and in inflammatory circuits which promote tumour growth and progression.
UR - http://www.scopus.com/inward/record.url?scp=2142662869&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=2142662869&partnerID=8YFLogxK
M3 - Conference contribution
C2 - 15027487
AN - SCOPUS:2142662869
SN - 9780470855102
VL - 256
T3 - Novartis Foundation Symposium
SP - 137
EP - 145
BT - Novartis Foundation Symposium
ER -