Inflammation-coagulation network: Are serine protease receptors the knot?

Giuseppe Cirino, Claudio Napoli, Mariarosaria Bucci, Carla Cicala

Research output: Contribution to journalArticlepeer-review

Abstract

Following an injury, the body recruits a mechanism to delimit and repair tissue damage; this phenomenon is known as inflammation. Among the several different pathways that are activated during this process, which is necessary for survival, activation of the coagulation pathway is a key feature. In fact, clinical changes in blood fluidity have been closely related to ongoing inflammation. Recent evidence suggests that serine protease receptors might play a major role in the host defence mechanism at the interface between coagulation and inflammation.

Original languageEnglish
Pages (from-to)170-172
Number of pages3
JournalTrends in Pharmacological Sciences
Volume21
Issue number5
DOIs
Publication statusPublished - May 1 2000

ASJC Scopus subject areas

  • Pharmacology
  • Toxicology

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