TY - JOUR
T1 - Inflammation in Obesity-Related Complications in Children
T2 - The Protective Effect of Diet and Its Potential Role as a Therapeutic Agent
AU - Calcaterra, Valeria
AU - Regalbuto, Corrado
AU - Porri, Debora
AU - Pelizzo, Gloria
AU - Mazzon, Emanuela
AU - Vinci, Federica
AU - Zuccotti, Gianvincenzo
AU - Fabiano, Valentina
AU - Cena, Hellas
PY - 2020/9/16
Y1 - 2020/9/16
N2 - Obesity is a growing health problem in both children and adults, impairing physical and mental state and impacting health care system costs in both developed and developing countries. It is well-known that individuals with excessive weight gain frequently develop obesity-related complications, which are mainly known as Non-Communicable Diseases (NCDs), including cardiovascular disease, type 2 diabetes mellitus, metabolic syndrome, non-alcoholic fatty liver disease, hypertension, hyperlipidemia and many other risk factors proven to be associated with chronic inflammation, causing disability and reduced life expectancy. This review aims to present and discuss complications related to inflammation in pediatric obesity, the critical role of nutrition and diet in obesity-comorbidity prevention and treatment, and the impact of lifestyle. Appropriate early dietary intervention for the management of pediatric overweight and obesity is recommended for overall healthy growth and prevention of comorbidities in adulthood.
AB - Obesity is a growing health problem in both children and adults, impairing physical and mental state and impacting health care system costs in both developed and developing countries. It is well-known that individuals with excessive weight gain frequently develop obesity-related complications, which are mainly known as Non-Communicable Diseases (NCDs), including cardiovascular disease, type 2 diabetes mellitus, metabolic syndrome, non-alcoholic fatty liver disease, hypertension, hyperlipidemia and many other risk factors proven to be associated with chronic inflammation, causing disability and reduced life expectancy. This review aims to present and discuss complications related to inflammation in pediatric obesity, the critical role of nutrition and diet in obesity-comorbidity prevention and treatment, and the impact of lifestyle. Appropriate early dietary intervention for the management of pediatric overweight and obesity is recommended for overall healthy growth and prevention of comorbidities in adulthood.
U2 - 10.3390/biom10091324
DO - 10.3390/biom10091324
M3 - Review article
C2 - 32947869
VL - 10
JO - Biomolecules
JF - Biomolecules
SN - 2218-273X
IS - 9
M1 - 1324
ER -