Inflammation, wound repair, and fibrosis: Reassessing the spectrum of tissue injury and resolution

Eric S. White, Alberto R. Mantovani

Research output: Contribution to journalArticle

Abstract

Estimates from various disease-specific registries suggest that chronic inflammatory and fibrotic disorders affect a large proportion of the world's population, yet therapies for these conditions are largely ineffective. Recent advances in our collective understanding of mechanisms underlying both physiological and pathological repair of tissue injury are informing new clinical approaches to deal with various human inflammatory and fibrotic diseases. This 2013 Annual Review Issue of The Journal of Pathology offers an up-to-date glimpse of ongoing research in the fields of inflammation, wound healing, and tissue fibrosis, and highlights novel pathways and mechanisms that may be exploited to provide newer, more effective treatments to patients worldwide suffering from these conditions.

Original languageEnglish
Pages (from-to)141-144
Number of pages4
JournalJournal of Pathology
Volume229
Issue number2
DOIs
Publication statusPublished - Jan 2013

Keywords

  • fibrosis
  • inflammation
  • wound healing

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Fingerprint Dive into the research topics of 'Inflammation, wound repair, and fibrosis: Reassessing the spectrum of tissue injury and resolution'. Together they form a unique fingerprint.

  • Cite this