Seizures following infliximab treatment are rare and no previous cases of infliximab-related seizures were reported with detailed description of EEG abnormalities and cerebral radiological findings. We describe a patient who acutely developed seizures temporally related to infliximab treatment, which disappeared after drug withdrawal. MRI showed an encephalopathy involving mainly cortical regions and EEG showed focal paroxysmal activity which completely disappeared a few days after infliximab withdrawal. No other explanation for seizures was discovered. The clear temporal association between seizures onset and infliximab treatment and the clinical and EEG improvement after drug withdrawal support the correlation with infliximab therapy. Infliximab-related seizures may be secondary to an encephalopathy involving cortico-subcortical regions.
|Translated title of the contribution||Infliximab-related seizures: A case report|
|Number of pages||3|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - Apr 2011|
ASJC Scopus subject areas
- Clinical Neurology