Influence of age and gender on complications of catheter ablation for atrial fibrillation

Giuseppe Stabile, Emanuele Bertaglia, Carlo Pappone, Sakis Themistoclakis, Claudio Tondo, Alessandro Zorzi, Matteo Anselmino

Research output: Contribution to journalArticlepeer-review


Background: Despite catheter ablation (CA) has become an accepted treatment option for symptomatic, drug-resistant atrial fibrillation (AF), safety of this procedure continues to be cause for concern. Objective: Aim of the present multicenter study was to assess the influence of age and gender on incidence and severity of early CA complications. Methods: From January 1, 2011 to December 31, 2011, data from 2,323 consecutive patients who underwent CA (mean age 59.1+10.9; 72.3% male) for AF in 29 Italian centres were collected. All complications occurring to the patients from admission to 30th post-procedural day were recorded. Results: Complications occurred in 94 patients (4.0%); of these 7 (0.30%) developed permanent sequelae. There was a significant trend toward a greater incidence of complications with increasing age-group. In particular, the incidence of complications was 35/1066 (3.3%) in patients <60 year-old vs 59/1257 (4.7%) in those > 60 year-old (p=0.03). All 7 patients with permanent sequeale were older than 60. Females had a higher incidence of complications both among younger [13/231 (5.6%) vs 22/915 (2.5%), p=0.02] and older patients [32/405 (7.9%) vs 27/739 (3.5%) p=0.001]. In subjects older than 60, 5/405 (1.2%) females and 2/176 (0.3%) males (p=0.04) suffered from permanent sequelae. Conclusions: Older patients and females are a subgroup at higher risk of complications during AF ablation. A particular care should be taken when performing CA in this clinical setting.

Original languageEnglish
Pages (from-to)10-14
Number of pages5
JournalJournal of Atrial Fibrillation
Issue number6
Publication statusPublished - Apr 1 2015

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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