Influence of autonomic impairment on blood-pressure and heart-rate scaling structures

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Self similarity is a promising tool for quantifying alterations in cardiovascular dynamics, although the effect of the autonomic control on the scaling structure of cardiovascular signals is still unknown. To address this issue, we studied spinal-cord injured subjects as a model of progressively impaired vascular control. We considered 24 able-bodied subjects (AB) and 23 paraplegics with lesion at different levels: between T12 and L 4 (N=7); T5 and T11 (N=9); and C6 and T4 (N=7). We recorded blood pressure and heart rate in three conditions characterized by increasing sympathetic activation: supine (SUP); sitting (SIT); and exercise (EXE). We calculated the scaling exponent of mean arterial pressure, HMAP, and of R-R interval, HRRI, by detrended fluctuation analysis. The sympathetic activation had different effects on the scaling exponent, depending on the lesion level. HRRI did not change significantly from SUP to SIT and to EXE in the AB and T 12-L4 group, while it increased in the T 5-T11 and C6-T4 groups. Also for HMAP sympathetic activation produced changes which depend on the level of the spinal lesion. In particular, our results suggest that heart-rate self similarity depends on the vascular sympathetic control, because it is altered by the spinal-cord lesion even when the cardiac neural control is intact.

Original languageEnglish
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages1446-1449
Number of pages4
DOIs
Publication statusPublished - 2006
Event28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06 - New York, NY, United States
Duration: Aug 30 2006Sep 3 2006

Other

Other28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
CountryUnited States
CityNew York, NY
Period8/30/069/3/06

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Blood pressure
Chemical activation

ASJC Scopus subject areas

  • Bioengineering

Cite this

Castiglioni, P., Merati, G., Veicsteinas, A., Parati, G., & Di Rienzo, M. (2006). Influence of autonomic impairment on blood-pressure and heart-rate scaling structures. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (pp. 1446-1449). [4029494] https://doi.org/10.1109/IEMBS.2006.259684

Influence of autonomic impairment on blood-pressure and heart-rate scaling structures. / Castiglioni, Paolo; Merati, Giampiero; Veicsteinas, Arsenio; Parati, Gianfranco; Di Rienzo, Marco.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2006. p. 1446-1449 4029494.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Castiglioni, P, Merati, G, Veicsteinas, A, Parati, G & Di Rienzo, M 2006, Influence of autonomic impairment on blood-pressure and heart-rate scaling structures. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings., 4029494, pp. 1446-1449, 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06, New York, NY, United States, 8/30/06. https://doi.org/10.1109/IEMBS.2006.259684
Castiglioni P, Merati G, Veicsteinas A, Parati G, Di Rienzo M. Influence of autonomic impairment on blood-pressure and heart-rate scaling structures. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2006. p. 1446-1449. 4029494 https://doi.org/10.1109/IEMBS.2006.259684
Castiglioni, Paolo ; Merati, Giampiero ; Veicsteinas, Arsenio ; Parati, Gianfranco ; Di Rienzo, Marco. / Influence of autonomic impairment on blood-pressure and heart-rate scaling structures. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2006. pp. 1446-1449
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